Case of Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Esophageal Cancer

이소연; 신성호; 이재혁; 안재성; 도병주; 장근두; 송헌호

Case of Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Esophageal Cancer

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식도암 환자에서 발생한항이뇨 호르몬 부적절 분비 증후군 1예

Type: Academic journal

Author: 이소연 신성호 이재혁 안재성 도병주 장근두 송헌호

Journal: The Korean Association Of Internal Medicine 대한내과학회지 대한내과학회지 제88권 제2호 KCI Candidated Journals

Published: 2015.1

Pages: 231 - 235 (5page)

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Case of Syndrome of Inappropriate Antidiuretic Hormone Secretion in a Patient with Esophageal Cancer

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Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) may be observed in various types of cancer, but is mainlyseen in small-cell carcinoma. It can also be caused by several chemotherapeutic agents. However, it is a very rare phenomenon inesophageal cancer or its treatment. We report here on a case of SIADH related to esophageal cancer treatment. A 55-year-old manreceived chemoradiotherapy (CRT) for esophageal cancer. After receiving CRT for 5 days, he complained of nausea, dizziness, andgeneral weakness, and his sodium level had dropped to 107 mEq/L. His volume status was clinically euvolemic and there were noedema or pigmentation. After hypertonic saline infusion, the sodium level increased and the symptoms improved. There have beenseveral reports of SIADH associated with malignancies or chemotherapy agents. However, to the best of our knowledge, this is thefirst Korean case of SIADH associated with esophageal cancer that occurred after cisplatin treatment.

#항이뇨 호르몬 부적절 분비 증후군 #식도암 #시스플라틴 #방사선 치료 #Syndrome of inappropriate secretion of antidiuretic hormone #SIADH) #Esophageal cancer #Cisplatin #Chemoradiotherapy

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Bartter FC / 1967 / The syndrome of inappropriate secretion of antidiuretic hormone / Am J Med 42 : 790 ~ 806

Endo C / 2013 / A case of consciousness disorder induced by the syndrome of inappropriate secretion of antidiuretic hormone following cisplatin and 5-fluorouracil chemotherap

Hicks P / 2012 / SIADH as a paraneoplastic syndrome of squamous cell carcinoma of the hypopharynx / Intern J Case Reports and Images (IJCRI) 3 : 12 ~ 15

Horio T / 2010 / Syndrome of inappropriate antidiuretic hormone secretion following adjuvant CDDP and 5-FU administration in a patient with esophageal carcinoma / Gan To Kaga

Kusuki M / 2004 / The syndrome of inappropriate antidiuretic hormone secretion associated with chemotherapy for hypopharyngeal cancer / Acta Otolaryngol Suppl 554 : 74 ~ 77

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