지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Nonalcoholic fatty liver disease (NAFLD) is composed of nonalcoholic fatty liver (NAFL), nonalcoholic steatohepatitis (NASH)and NASH related cirrhosis and these are defined by histological findings. These diseases have absolutely typical and differentclinical findings and natural courses respectively. NAFL generally has benign process however; NASH and NASH related cirrhosishave an increased risk for liver-related morbidity and mortality. So, the accurate diagnosis and differentiation of steatohepatitis oradvanced fibrosis are essential in the management of patient and the prediction of prognosis. The gold-standard of diagnosis ofNAFLD is liver biopsy however; it has some limitations in clinical practice. So many studies have been done to find outnoninvasive diagnostic methods. These methods can be divided into 2 groups: those that predict the presence of NASH and thatpredict the presence of advanced fibrosis. This paper provides an overview of various noninvasive methods for detecting NAFLDand their clinical meanings in clinical practice.
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참고문헌 (22)
참고문헌 신청
Adams LA / 2005 / The natural history of nonalcoholic fatty liver disease: a population-based cohort study / Gastroenterology 129 : 113 ~ 121
Bae JC / 2010 / Impact of nonalcoholic fatty liver disease on insulin resistance in relation to HbA1c levels in nondiabetic subjects / Am J Gastroenterol 105 : 2389 ~ 2395
Chalasani N / 2012 / The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, Ameri
Choi SY / 2009 / The relation between nonalcoholic fatty liver disease and the risk of coronary heart disease in Koreans / Am J Gastroenterol 104 : 1953 ~ 1960
Ekstedt M / 2006 / Long-term follow-up of patients with NAFLD and elevated liver enzymes / Hepatology 44 : 865 ~ 873
Bae JC / 2010 / Impact of nonalcoholic fatty liver disease on insulin resistance in relation to HbA1c levels in nondiabetic subjects / Am J Gastroenterol 105 : 2389 ~ 2395
Chalasani N / 2012 / The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, Ameri
Choi SY / 2009 / The relation between nonalcoholic fatty liver disease and the risk of coronary heart disease in Koreans / Am J Gastroenterol 104 : 1953 ~ 1960
Ekstedt M / 2006 / Long-term follow-up of patients with NAFLD and elevated liver enzymes / Hepatology 44 : 865 ~ 873
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