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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background/Aims: Most scrub typhus patients have normal electrocardiography (ECG) findings. Recently, however, several caseswith ECG changes were reported. However, few studies have examined the ECG changes in scrub typhus.
Methods: The ECG and demographic data of patients infected with Orientia tsutsugamushi seen at Dongsan Medical Center fromJanuary 2008 to June 2012 were reviewed retrospectively. Patients with pre-existing cardiac disease were excluded. The initial andfollow-up ECG findings, demographic characteristics, and laboratory findings was examined.
Results: The group in which the initial ECG showed an arrhythmia had a higher blood urea nitrogen (BUN) level than the normaland ischemic groups (median 26.0 vs. 15.0 vs. 15.5 mg/dL, p = 0.041). The group with a sustained abnormality in the follow-upECG had higher BUN (median 17.0 vs. 15.0 mg/dL, p = 0.022) and creatinine (median 1.30 vs. 0.90 mg/dL, p = 0.026) levels thanthe normal ECG group. In addition, the group with a sustained abnormality in the follow-up ECG had a higher rate of intensive careunit (ICU) admission (30.8% vs. 5.3%, p = 0.015) and longer treatment period (average 9 vs. 6 days, p = 0.027) than the othergroups.
Conclusions: In our study, more than 30% of the patients with scrub typhus showed ECG abnormalities. Those with an arrhythmicECG change on presentation had high BUN levels. The sustained ECG abnormality group had high BUN and creatinine levels, andan increased ICU admission rate and length of stay. We should pay attention to the ECG findings on presentation and during thetreatment of scrub typhus.
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참고문헌 (17)
참고문헌 신청
Chien RN / 1995 / Granulomatous hepatitis associated with scrub typhus / J Gastroenterol Hepatol 10 : 484 ~ 487
Fang CY / 1977 / Electrocardiographic changes in scrub typhus patients / Southeast Asian J Trop Med Public Health 8 : 503 ~ 509
Holliday MA / 1959 / The renal lesions of electrolyte imbalance: II. the combined effect on renal architecture of phosphate loading and potassium depletion / J Exp Med 110 :
Kantipong P / 1996 / Infection with human immunodeficiency virus does not influence the clinical severity of scrub typhus / Clin Infect Dis 23 : 1168 ~ 1170
Kim HY / 2004 / Recent tendency of tsutsugamushi disease in Korea / Korean J Med 67 (2) : 516 ~ 522
Fang CY / 1977 / Electrocardiographic changes in scrub typhus patients / Southeast Asian J Trop Med Public Health 8 : 503 ~ 509
Holliday MA / 1959 / The renal lesions of electrolyte imbalance: II. the combined effect on renal architecture of phosphate loading and potassium depletion / J Exp Med 110 :
Kantipong P / 1996 / Infection with human immunodeficiency virus does not influence the clinical severity of scrub typhus / Clin Infect Dis 23 : 1168 ~ 1170
Kim HY / 2004 / Recent tendency of tsutsugamushi disease in Korea / Korean J Med 67 (2) : 516 ~ 522
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