지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
A full haplotype mismatch or mismatched unrelated donor transplantation nowadays are well being focused on, as main alternative donor tools for acute leukemia patients in desperate need of allogeneic blood and marrow transplantation (BMT), the ability to overcome various posttransplant complications by adopting the T-cell replete technique in reality. Increasing numbers of allogeneic BMT in good clinical status are largely because it’s the best post-remission therapy especially for many patients with acute leukemias. Due to the problems of unavailable donors at appropriate clinical condition and the process of long duration of donor searching step with relatively much higher cost, some of physicians have indulged in haploidentical BMT rather than mismatched unrelated BMT. Both myeloablative and reduced intensity conditioning regimens for mismatched BMT with T-cell replete or T-cell depletion method have been exploited worldwide. Most of all, Asian countries have experienced lower rates of severe acute and chronic GvHD, graft failure, and impressively low transplant-related mortality with longer follow-up duration. Also, we need many future trials to compare outcomes between these two transplant modalities with cord blood transplant in various diseased patient populations.
목차
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참고문헌 (20)
참고문헌 신청
Akatsuka Y / 2003 / Disparity for a newly identified minor histocompatibility antigen, HA-8, correlates with acute graft-versus-host disease after haematopoietic stem cell t
Arcese W / 2011 / Algorithm for donor selection in 2011 / Curr Opin Hematol 18 : 401 ~ 407
Ballen KK / 2012 / Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant / Blood 119 : 1972 ~ 1980
Buckner CD / 1970 / Allogeneic marrow engraftment following whole body irradiation in a patient with leukemia / Blood 35 : 741 ~ 750
Cho BS / 2012 / Comparison of allogeneic stem cell transplantation from familial-mismatched/haploidentical donors and from unrelated donors in adults with high-risk acute my
Arcese W / 2011 / Algorithm for donor selection in 2011 / Curr Opin Hematol 18 : 401 ~ 407
Ballen KK / 2012 / Selection of optimal alternative graft source: mismatched unrelated donor, umbilical cord blood, or haploidentical transplant / Blood 119 : 1972 ~ 1980
Buckner CD / 1970 / Allogeneic marrow engraftment following whole body irradiation in a patient with leukemia / Blood 35 : 741 ~ 750
Cho BS / 2012 / Comparison of allogeneic stem cell transplantation from familial-mismatched/haploidentical donors and from unrelated donors in adults with high-risk acute my
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