지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background/Aims: Kidney transplantation (KT) is the best treatment for end-stage renal disease patients. Although previousstudies have demonstrated that the clinical outcome following living related (LR) KT is better than that following unrelated (LUR)KT in ABO-compatible KT recipients, recent studies showed no differences in clinical outcomes between the two treatments. Inthis study, we compared the clinical outcomes of LR and LUR KT in ABO-incompatible KT recipients.
Methods: From January 2011 to August 2013, 19 cases of ABO-incompatible KT were analyzed retrospectively. Eight kidneys (7cases of parent-offspring and 1 case of siblings, Group 1) were donated from living-related donors and 11 (all spousal donors,Group 2) from living-unrelated donors. We investigated patient survival, graft survival, acute rejection, graft function, and complications.
Results: On Kaplan-Meier analysis, patient and graft survival during follow-up were 87.5% and 87.5% in Group 1; both were100% in Group 2. Acute rejection, graft function, and medical and surgical complications were not significantly different betweenthe two groups.
Conclusions: The short-term clinical outcomes between LR and LUR KT in ABO-incompatible KT recipients were equivalent. Most domestic cases of LUR KT are from spousal donors and the spousal donor will be a major donor in ABO-incompatible KT patients.
목차
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참고문헌 (15)
참고문헌 신청
Alexandre GP / 1985 / Human ABO-incompatible living donor renal homografts / Neth J Med 28 : 231 ~ 234
Audard V / 2008 / Renal transplantation from extended criteria cadaveric donors: problems and perspectives overview / Transpl Int 21 : 11 ~ 17
Holechek MJ / 2003 / Expanding the living organ donor pool: positive crossmatch and ABO incompatible renal transplantation / Nephrol Nurs J 30 : 195 ~ 204
Hume DM / 1955 / Experiences with renal homotransplantation in the human: report of nine cases / J Clin Invest 34 : 327 ~ 382
Ichimaru N / 2008 / Japan's experience with living- donor kidney transplantation across ABO barriers / Nat Clin Pract Nephrol 4 : 682 ~ 692
Audard V / 2008 / Renal transplantation from extended criteria cadaveric donors: problems and perspectives overview / Transpl Int 21 : 11 ~ 17
Holechek MJ / 2003 / Expanding the living organ donor pool: positive crossmatch and ABO incompatible renal transplantation / Nephrol Nurs J 30 : 195 ~ 204
Hume DM / 1955 / Experiences with renal homotransplantation in the human: report of nine cases / J Clin Invest 34 : 327 ~ 382
Ichimaru N / 2008 / Japan's experience with living- donor kidney transplantation across ABO barriers / Nat Clin Pract Nephrol 4 : 682 ~ 692
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