지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Non-Helicobacter pylori, non-NSAID peptic ulcer disease, termed idiopathic peptic ulcer disease (IPUD), is being increasinglyrecognized. Current data suggest that the relative proportion of patients with IPUD among those with peptic ulcers has beenincreasing for the past decade in both the West and East, while the prevalence of H. pylori ulcers has decreased. Potential causativeor risk factors of IPUD include cigarette smoking, genetic predisposition, psychological factors, infections other than H. pylori,non-NSAID drugs or toxins, systemic inflammatory disease, and local mucosal defects. Diagnosis is made after confident exclusionof H. pylori infection by at least two different standard tests and accurate exclusion of unrecognized or surreptitious NSAID use bycareful history taking and serologic assay. IPUD is characterized by higher complication and recurrence rates than other forms ofpeptic ulcer disease and has become a main cause of refractory ulcer disease. Maintenance therapy using proton pump inhibitorsmay be required at higher doses and for longer durations than in H. pylori- or NSAID-associated peptic ulcer diseases. Welldesignednationwide epidemiologic studies are required to fully elucidate this emerging condition.
목차
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참고문헌 (24)
참고문헌 신청
Arroyo MT / 2004 / The prevalence of peptic ulcer not related to Helicobacter pylori or nonsteroidal anti-inflammatory drug use is negligible in southern Europe / Helicobact
Boulos PB / 2002 / Possible absence of Helicobacter pylori in the early stages of duodenal ulceration / QJM 95 : 749 ~ 752
Bytzer P / 2001 / Danish Ulcer Study Group. Helicobacter pylori-negative duodenal ulcers: prevalence, clinical characteristics, and prognosis: results from a randomized tria
Chung IS / 2012 / Peptic ulcer disease in Korea / Korean J Helicobacter Up Gastrointest Res 12 : 19 ~ 22
Ciociola AA / 1999 / Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated / Am J Gastroenterol 94 : 1834
Boulos PB / 2002 / Possible absence of Helicobacter pylori in the early stages of duodenal ulceration / QJM 95 : 749 ~ 752
Bytzer P / 2001 / Danish Ulcer Study Group. Helicobacter pylori-negative duodenal ulcers: prevalence, clinical characteristics, and prognosis: results from a randomized tria
Chung IS / 2012 / Peptic ulcer disease in Korea / Korean J Helicobacter Up Gastrointest Res 12 : 19 ~ 22
Ciociola AA / 1999 / Helicobacter pylori infection rates in duodenal ulcer patients in the United States may be lower than previously estimated / Am J Gastroenterol 94 : 1834
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