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Photodynamic Therapy Followed by Left Hepatectomy Used to Treat an Intraductal Papillary Mucinous Neoplasm of the Bile Duct
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광역학 치료 후 간 좌엽절제술이 가능하였던담관 내 유두상 점액 종양 1예

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Photodynamic Therapy Followed by Left Hepatectomy Used to Treat an Intraductal Papillary Mucinous Neoplasm of the Bile Duct
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Mucin-hypersecreting bile duct tumors, which closely resemble intraductal papillary mucinous neoplasms of the pancreas, arerare, and both the clinical features and management thereof are poorly understood. As the biliary tract and the pancreas share a commonorigin, the two diseases may exhibit homologous histopathological features. Certain intraductal papillary tumors of the bileduct are associated with production of large amounts of mucin that disturb bile flow and cause severe biliary dilatation, obstructivejaundice, and cholangitis. Herein, we report on a patient with an extensive intraductal papillary mucinous neoplasm of the bile duct,involving both the right and left intrahepatic ducts. The ducts were subjected to photodynamic therapy, followed by lefthepatectomy. The surgical specimen revealed an adenocarcinoma with a negative resection margin. Photodynamic therapy of theintrahepatic ducts was well-tolerated in the present case, and may serve as a useful therapeutic option for selected patients with intraductalpapillary mucinous neoplasms of the bile duct.

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