지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The coexpression of cortical and medullary features in a single adrenal cortical cell has been recognized, leading to terms such as cortico-medullary cells. Here, we reported a case of adrenocortical adenoma consisting of cortico-medullary cells that clinically mimicked pheochromocytoma. A 52-year-old woman was admitted to our hospital complaining of an 8-month history of paroxysmal palpitation with refractory hypertension. A 24-hour urine study revealed increased norepinephrine and metanephrine levels. Computed tomography of the abdomen revealed a 1.0×0.9-cm mass in the left adrenal gland. The patient subsequently underwent unilateral laparoscopic adrenalectomy for a presumptive pheochromocytoma. Light microscopic findings of the left adrenal mass indicated an adrenocortical adenoma, but electron microscopy identified lipid vacuoles and smooth endoplasmic reticulum, along with dense core neurosecretory granules, so-called cortico-medullary cells. This is the first report of the detection of cortico-medullary cells in adrenocortical adenoma presenting as pheochromocytoma in Korea. (Korean J Med 75:479-483, 2008)
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Alsabeh R / 1995 / Adrenal cortical tumors clinically mimicking pheochromocytoma / Am J Clin Pathol 104 : 382 ~ 390
Eranko O / 1960 / Electron microscopic observation on the adrenal medulla of the rat / Acta Pathol Microbiol Scan 50 : 126 ~ 132
Haak HR / 1995 / Neuroendocrine differentiation of adrenocortical tumors / Cancer 75 : 860 ~ 864
Hsiao RJ / 1991 / Chromogranin A storage and secretion: sensitivity and specificity for the diagnosis of pheochromocytoma / Medicine 70 : 33 ~ 45
Ivsic T / 2002 / Adrenocortical adenoma with adrenalin-type neurosecretory granules clinically mimicking a pheochromocytoma / Arch Pathol Lab Med 126 : 1530 ~ 1533
Eranko O / 1960 / Electron microscopic observation on the adrenal medulla of the rat / Acta Pathol Microbiol Scan 50 : 126 ~ 132
Haak HR / 1995 / Neuroendocrine differentiation of adrenocortical tumors / Cancer 75 : 860 ~ 864
Hsiao RJ / 1991 / Chromogranin A storage and secretion: sensitivity and specificity for the diagnosis of pheochromocytoma / Medicine 70 : 33 ~ 45
Ivsic T / 2002 / Adrenocortical adenoma with adrenalin-type neurosecretory granules clinically mimicking a pheochromocytoma / Arch Pathol Lab Med 126 : 1530 ~ 1533
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