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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
In-stent restenosis has been reduced significantly after introduction of drug eluting stent (DES). But concern of long-term safety has emerged because of inappropriate neointimal coverage over stent related with cytotoxic drug and polymer. Recently, non-cardiac surgery after DES implantation is increasing and use of anti-platelet agent during operation might be problematic. Non-cardiac surgery might increase the risk of stent thrombosis, which was related with myocardial infarction and death, particularly in DES. Preoperative discontinuation of dual-antiplatelet therapy (DAT) and early surgery after stent implantation have been well known factors of perioperative stent thrmbosis. Thus, current guideline for anti-platelet therapy in non-cardiac surgery was established in patients after balloon angioplasty and bare metal stent based on duration of DAT according to the period of complete endothelization and neointimal growth after stent implantation. But, there are controversies and little evidence in DES for timing and use of DAT to reduce the stent thrombosis in non-cardiac surgery. Therefore, I reviewed the existing data about stent thrombosis after noncardiac surgery, the impact of delay from surgery and discontinuation of DAT. Based on these published data, I suggested recommendations for patients who require noncardiac surgery after DES. (Korean J Med 75:392-397, 2008)
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
/ 2002 / Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients / BMJ 324
Bourassa MG / 1991 / Clinical, physiologic, anatomic and procedural factors predictive of restenosis after percutaneous transluminal coronary angioplasty / J Am Coll Cardiol
Carrozza JP, Jr / 1992 / Angiographic and clinical outcome of intracoronary stenting: immediate and long-term results from a large single-center experience / J Am Coll Cardio
Chassot PG / 2007 / Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction / Br J Anaesth 99 : 316 ~ 328
Cutlip DE / 2001 / Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials / Circulation 103 : 1967 ~ 1971
Bourassa MG / 1991 / Clinical, physiologic, anatomic and procedural factors predictive of restenosis after percutaneous transluminal coronary angioplasty / J Am Coll Cardiol
Carrozza JP, Jr / 1992 / Angiographic and clinical outcome of intracoronary stenting: immediate and long-term results from a large single-center experience / J Am Coll Cardio
Chassot PG / 2007 / Perioperative antiplatelet therapy: the case for continuing therapy in patients at risk of myocardial infarction / Br J Anaesth 99 : 316 ~ 328
Cutlip DE / 2001 / Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent clinical trials / Circulation 103 : 1967 ~ 1971
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