지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 288 - 296 (9page)
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초록· 키워드
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Background: The aim of this study was to assess the relationship between acute physiologic and chronic health examination (APACHE) II and sequential organ failure assessment (SOFA) scores and outcomes of post-cardiac arrest patients treated with therapeutic hypothermia (TH).
Methods: Out-of-hospital cardiac arrest (OHCA) survivors treated with TH between January 2010 and December 2012 were retrospectively evaluated. We captured all components of the APACHE II and SOFA scores over the first 48 hours after intensive care unit (ICU) admission (0 h). The primary outcome measure was in-hospital mortality and the secondary outcome measure was neurologic outcomes at the time of hospital discharge. Receiver-operating characteristic and logistic regression analysis were used to determine the predictability of outcomes with serial APACHE II and SOFA scores.
Results: A total of 138 patients were enrolled in this study. The area under the curve (AUC) for APACHE II scores at 0 h for predicting in-hospital mortality and poor neurologic outcomes (cerebral performance category: 3-5) was more than 0.7, and for SOFA scores from 0 h to 48 h the AUC was less than 0.7. Odds ratios used to determine associations between APACHE II scores from 0 h to 48 h and in-hospital mortality were 1.12 (95% confidence interval [CI], 1.03-1.23), 1.13 (95% CI, 1.04-1.23), and 1.18 (95% CI, 1.07-1.30).
Conclusions: APACHE II, but not SOFA score, at the time of ICU admission is a modest predictor of in-hospital mortality and poor neurologic outcomes at the time of hospital discharge for patients who have undergone TH after return of spontaneous circulation following OHCA.
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참고문헌 (20)
참고문헌 신청
Adrie C / 2006 / Predicting survival with good neurological recovery at hospital admission after successful resuscitation of out-of-hospital cardiac arrest: the OHCA score /
Akobeng AK / 2007 / Understanding diagnostic tests 3: receiver operating characteristic curves / Acta Paediatr 96 : 644 ~ 647
Bernard SA / 2002 / Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia / N Engl J Med 346 : 557 ~ 563
Bohnen JM / 1988 / APACHE II score and abdominal sepsis. A prospective study / Arch Surg 123 : 225 ~ 229
Cummins RO / 1991 / Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest:the Utstein style. A statement for health professionals from a t
Akobeng AK / 2007 / Understanding diagnostic tests 3: receiver operating characteristic curves / Acta Paediatr 96 : 644 ~ 647
Bernard SA / 2002 / Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia / N Engl J Med 346 : 557 ~ 563
Bohnen JM / 1988 / APACHE II score and abdominal sepsis. A prospective study / Arch Surg 123 : 225 ~ 229
Cummins RO / 1991 / Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest:the Utstein style. A statement for health professionals from a t
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