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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 175 - 181 (7page)
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초록· 키워드
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The aim of this study was to provide a basis for the molecular mechanism underlying the pharmacological action of ethanol. We studied the effects of 1-propanol on the location of n-(9-anthroyloxy)palmitic acid or stearic acid (n-AS) within the phospholipids of synaptosomal plasma membrane vesicles (SPMV). The SPMV were isolated from the bovine cerebral cortex and liposomes of total lipids (SPMVTL) and phospholipids (SPMVPL). 1-Propanol increased the rotational mobility of inner hydrocarbons, while decreasing the mobility of membrane interface, in native and model membranes. The degree of rotational mobility varied with the number of carbon atoms at positions 16, 12, 9, 6 and 2 in the aliphatic chain of phospholipids in the neuronal and model membranes. The sensitivity of increasing or decreasing rotational mobility of hydrocarbon interior or surface by 1-propanol varied with the neuronal and model membranes in the following order: SPMV, SPMVPL and SPMVTL.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Angelova ML / 1987 / Lipid swelling and liposome formation on solid surfaces in external electric fields / Prog Colloid Polym Sci 73 : 48 ~ 56
Angelova ML / 1992 / Preparation of giant vesicles by external AC fields, kinetics and application / Prog Colloid Polym Sciz 89 : 127 ~ 131
Bartlett GR / 1959 / Phosphorous assay in column chromatography / J Biol Chem 234 : 466 ~ 468
D D Lasic / 1988 / The mechanism of vesicle formation / Biochemical Journal 256 (1) : 1 ~ 11
Franklin S. Abrams / 2002 / Extension of the parallax analysis of membrane penetration depth to the polar region of
Angelova ML / 1992 / Preparation of giant vesicles by external AC fields, kinetics and application / Prog Colloid Polym Sciz 89 : 127 ~ 131
Bartlett GR / 1959 / Phosphorous assay in column chromatography / J Biol Chem 234 : 466 ~ 468
D D Lasic / 1988 / The mechanism of vesicle formation / Biochemical Journal 256 (1) : 1 ~ 11
Franklin S. Abrams / 2002 / Extension of the parallax analysis of membrane penetration depth to the polar region of
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