지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 77 - 83 (7page)
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초록· 키워드
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We investigated the pulpal response to direct pulp capping in rat molar teeth using mineral trioxide aggregate (MTA)and calcium hydroxide (CH). A palatal cavity was prepared in rat maxillary molar teeth. Either MTA or CH was placed on the exposed pulp and all cavities were restored with composite. Rats were sacrificed for histological evaluation after 12 hours and at 2, 7, 14 and 21 days. In both the MTA and CH groups, reparative dentin formation was clearly observed on histology after 14 days. The MTA-capped pulps were found to be mostly free from inflammation, and hard tissue of a tubular consistent barrier was observed. In contrast, in CH-capped teeth, excessive formation of reparative dentin toward residual pulp was evident. The pulpal cell response beneath the reparative dentin layer was examined by immunofluorescence using antibodies against DSP. After 2 days, a few DSP immunopositive cells, most of which showed a cuboidal shape, appeared beneath the predentin layer. At 7 days, DSP-immunopositive cells with columnar odontoblast-like cells were seen beneath the newly formed hard tissues. At 14 and 21 days, DSP was more abundant in the vicinity of the odontoblastic process along the dentinal tubules than in the mineralized reparative dentin. The CH group showed strong expression patterns in terms of DSP immunoreactivity. Our results thus indicate that MTA may be a more effective pulp capping material as it induces the differentiation of odontoblast-like cells and the formation of reparative dentin without the loss of residual pulp functions.
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참고문헌 (24)
참고문헌 신청
Barthel CR / 2000 / Pulp capping of carious exposures: treatment outcome after 5 and 10 years: a retrospective study / J Endod 26 : 525 ~ 528
Butler WT / 1991 / Sialoproteins of bone and dentin / J Biol Buccale 19 : 83 ~ 89
Butler WT / 1995 / Dentin matrix proteins and dentinogenesis / Connect Tissue Res 33 : 59 ~ 65
Faraco IM Jr / 2001 / Response of the pulp of dogs to capping with mineral trioxide aggregate or a calcium hydroxide cement / Dent Traumatol 17 : 163 ~ 166
Ford TR / 1996 / Using mineral trioxide aggregate as a pulp-capping material / J Am Dent Assoc 127 : 1491 ~ 1494
Butler WT / 1991 / Sialoproteins of bone and dentin / J Biol Buccale 19 : 83 ~ 89
Butler WT / 1995 / Dentin matrix proteins and dentinogenesis / Connect Tissue Res 33 : 59 ~ 65
Faraco IM Jr / 2001 / Response of the pulp of dogs to capping with mineral trioxide aggregate or a calcium hydroxide cement / Dent Traumatol 17 : 163 ~ 166
Ford TR / 1996 / Using mineral trioxide aggregate as a pulp-capping material / J Am Dent Assoc 127 : 1491 ~ 1494
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