지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 240 - 244 (5page)
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초록· 키워드
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Background: The study evaluated the clinical efficacy of a multi-parameter realtime polymerase chain reaction (PCR) test for patients with central venous catheterrelated bloodstream infection (CRBSI).
Materials and Methods: Thirty five patients suspected to have CRBSI were enrolled. The SeptiFast™ (SF) multi-parameter real-time PCR test (Roche Diagnostics, Germany) and blood culture were performed and results were compared.
Results: The turn-around time for the SF test and blood culture was 32.6±28.9 hours and 115.8±23.5 hours, respectively. Among the 70 blood samples, the positive rates of SF test and blood culture were 34.3% and 27.1%, respectively, and the agreement rate was 62.9%. Gram-positive bacteria were detected in 10 patients with blood culture and 11 patients with SF test. Gram-negative bacteria were detected in one patient with a blood culture and in seven patients with SF test. Candida was not detected in blood culture but was detected in two patients by the SF test.
Conclusions: SF test was faster and more sensitive for the detection of blood pathogens than blood culture. It provides a more sensitive detection of gramnegative and Candida in blood than does blood culture testing.
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참고문헌 (17)
참고문헌 신청
Angus DC / 2001 / Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care / Crit Care Med 29 : 1303 ~ 1310
Dimopoulos G / 2009 / Approach to the febrile patient in the ICU / Infect Dis Clin North Am 23 : 471 ~ 484
Klaerner HG / 2000 / Failure of an automated blood culture system to detect nonfermentative gram-negative bacteria / J Clin Microbiol 38 : 1036 ~ 1041
Lehmann LE / 2008 / A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples / Med Microbiol Imm
Maki DG / 2006 / The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies / Mayo Clin Proc 8
Dimopoulos G / 2009 / Approach to the febrile patient in the ICU / Infect Dis Clin North Am 23 : 471 ~ 484
Klaerner HG / 2000 / Failure of an automated blood culture system to detect nonfermentative gram-negative bacteria / J Clin Microbiol 38 : 1036 ~ 1041
Lehmann LE / 2008 / A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples / Med Microbiol Imm
Maki DG / 2006 / The risk of bloodstream infection in adults with different intravascular devices: a systematic review of 200 published prospective studies / Mayo Clin Proc 8
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