지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 243 - 250 (8page)
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Background: Although it is known that losing weight has an effect on the treatment of non-alcoholic fatty liver disease, the studies that show how losing weight affects the non-alcoholic fatty liver disease for the normal weight male adults are limited so far. In this study, we set body mass index as criteria and investigated how the weight changes for 4 years makes an impact on the risk of non-alcoholic fatty liver disease for the male adults who have the normal body mass index.Methods: From January to December of 2004, among the normal weight male adults who had general check-up at the Health Promotion Center of Ulsan University Hospital, 180 people (average age, 47.4 ± 4.61 years) who were diagnosed with fatty liver through abdominal ultrasonography were included in this study and were observed according to the variety of data and ultrasonography after 4 years (2008). People who had a history of drinking more than 140 g of alcohol per week or who had a past medical history were excluded from the analysis. The weight change of subjects was calculated using the formula ‘weight change = weight of 2008 (kg) - weight of 2004 (kg)’ and classified into three groups, loss group (≤-3.0 kg), stable group (-2.9 to 2.9 kg), and gain group (≥3.0 kg). The odds for disappearance of non-alcoholic fatty liver disease in those three different groups were compared.Results: Among 180 subjects, compared with stable group (67.2%, 121 subjects), loss group (11.7%, 21 subjects) showed 18.37-fold increase in the odds of disappearance of non-alcoholic fatty liver disease (95% confidence interval [CI], 4.34 to 77.80) and gain group (21.1%, 38 subjects) showed 0.28-fold decrease in the odds of disappearance of non-alcoholic fatty liver disease (95% CI, 0.10 to 0.83).Conclusion: Even for the normal weight people, losing weight has an effect on the improvement of non-alcoholic fatty liver disease.
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참고문헌 (20)
참고문헌 신청
American Gastroenterological Association / 2002 / American Gastroenterological Association medical position statement: nonalcoholic fatty liver disease / Gastroenterology 123
Angelico F / 2003 / Non-alcoholic fatty liver syndrome: a hepatic consequence of common metabolic diseases / J Gastroenterol Hepatol 18 : 588 ~ 594
Bayard M / 2006 / Nonalcoholic fatty liver disease / Am Fam Physician 73 : 1961 ~ 1968
Bugianesi E / 2002 / Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma / Gastroenterology 123 : 134 ~ 140
Chalasani N / 2012 / The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Associat
Angelico F / 2003 / Non-alcoholic fatty liver syndrome: a hepatic consequence of common metabolic diseases / J Gastroenterol Hepatol 18 : 588 ~ 594
Bayard M / 2006 / Nonalcoholic fatty liver disease / Am Fam Physician 73 : 1961 ~ 1968
Bugianesi E / 2002 / Expanding the natural history of nonalcoholic steatohepatitis: from cryptogenic cirrhosis to hepatocellular carcinoma / Gastroenterology 123 : 134 ~ 140
Chalasani N / 2012 / The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Associat
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