지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 372 - 376 (5page)
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Staphylococcus lugdunensis is a Gram-positive, coagulase-negative Staphylococcus (CNS) species that is found as a skin commensal and has been implicated in fulminant invasive diseases such as infective endocarditis. S. lugudunensis infections resemble Staphylococcus aureus infections in terms of virulence, tissue destruction and clinical course. Although correct identification and determination of the susceptibility profile are important, some commercial systems may misidentify S. lugdunensis . We report a case of native valve infective endocarditis caused by S. lugdunensis , which was misidentified by the Vitek 2system but identified correctly by 16S ribosomal RNA (rRNA) gene sequencing in a 72-year-old male patient. The patient had multiple vegetations on his mitral valve, and the largest one was found on the posterior mitral valve leaflet. It was 2.5cm in size and hypermobile. Diffuse valvular abscess was also observed. He had persistent bacteremia for appoximately 8 days, which was resolved after immediate surgery and antibiotic therapy. When a patient with severe sepsis syndrome grows S. aureus or CNS other than S. lugdunensis on a commercial automatic culture system, the possibility of S. lugdunensis should be considered and further confirmatory testing such as 16S rRNA sequencing may be very useful.
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참고문헌 (20)
참고문헌 신청
Anguera I / 2005 / Staphylococcus lugdunensis infective endocarditis: description of 10 cases and analysis of native valve, prosthetic valve, and pacemaker lead endocarditis
Bosshard PP / 2003 / Etiologic diagnosis of infective endocarditis by broad-range polymerase chain reaction: a 3-year experience / Clin Infect Dis 37 : 167 ~ 172
Choi SH / 2010 / Incidence, Characteristics, and Outcomes of Staphylococcus lugdunensis Bacteremia / JOURNAL OF CLINICAL MICROBIOLOGY 48 (9) : 3346 ~ 3349
Clinical and Laboratory Standards Institute / 2007 / Performance standards for antimicrobial susceptibility testing: 16th informational supplement
De Paulis AN / 2003 / Five-test simple scheme for species-level identification of clinically significant coagulase-negative staphylococci / J Clin Microbiol 41 : 1219 ~ 1224
Bosshard PP / 2003 / Etiologic diagnosis of infective endocarditis by broad-range polymerase chain reaction: a 3-year experience / Clin Infect Dis 37 : 167 ~ 172
Choi SH / 2010 / Incidence, Characteristics, and Outcomes of Staphylococcus lugdunensis Bacteremia / JOURNAL OF CLINICAL MICROBIOLOGY 48 (9) : 3346 ~ 3349
Clinical and Laboratory Standards Institute / 2007 / Performance standards for antimicrobial susceptibility testing: 16th informational supplement
De Paulis AN / 2003 / Five-test simple scheme for species-level identification of clinically significant coagulase-negative staphylococci / J Clin Microbiol 41 : 1219 ~ 1224
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