지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 291 - 295 (5page)
이용수
초록· 키워드
오류제보하기
Background: Carbohydrate-deficient transferrin (CDT) is a useful biomarker to identify excessive alcohol con-sumption; however, few studies have validated the %CDT cut-off value in elderly men. This study estimated the op-timal %CDT cut-off value that could identify excessive alcohol consumption in men aged ≥65 years.Methods: This retrospective study included 120 men who visited the department of family medicine at Chungnam National University Hospital for health check-up between January 2010 and August 2013. At-risk drinking included heavy- and binge drinking. Heavy drinking was defined as more than seven standard drinks/wk, and binge drink-ing was defined as more than three standard drinks/d. The cut-off %CDT values for at-risk drinking were deter-mined using receiver operating characteristic (ROC) curves.Results: Based on the ROC curves, the optimal %CDT cut-off values in ≥65-year-old men were 1.95% for at-risk drinking, 1.81% for heavy drinking, and 2.07% for binge drinking. The sensitivity, specificity, and positive and nega-tive predictive values were 58.7%, 83.6%, 69.2%, and 76.2% for at-risk drinking, respectively. The AUROC were >0.7 for all three evaluated cut-offs.Conclusion: Our results suggest that the %CDT cut-off value for at-risk drinking in elderly Korean men (≥65 years) should be readjusted to a lower value of 1.95%.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Agelink MW / 1998 / Sensitivity of carbohydrate-deficient transferrin(CDT)in relation to age and duration of abstinence / Alcohol Alcohol 33 : 164 ~ 167
Behrens UJ / 1988 / Changes in carbohydrate-deficient transferrin levels after alcohol withdrawal / Alcohol Clin Exp Res 12 : 539 ~ 544
Bianchi V / 2010 / Use of carbohydrate-deficient transferrin(CDT)and a combination of GGT and CDT(GGT-CDT)to assess heavy alcohol consumption in traffic medicine / Alcohol Al
Bortolotti F / 2006 / Carbohydrate-deficient transferrin(CDT)as a marker of alcohol abuse : a critical review of the literature 2001-2005 / J Chromatogr B Analyt Technol Biom
Dawson DA / 2005 / Quantifying the risks associated with exceeding recommended drinking limits / Alcohol Clin Exp Res 29 : 902 ~ 908
Behrens UJ / 1988 / Changes in carbohydrate-deficient transferrin levels after alcohol withdrawal / Alcohol Clin Exp Res 12 : 539 ~ 544
Bianchi V / 2010 / Use of carbohydrate-deficient transferrin(CDT)and a combination of GGT and CDT(GGT-CDT)to assess heavy alcohol consumption in traffic medicine / Alcohol Al
Bortolotti F / 2006 / Carbohydrate-deficient transferrin(CDT)as a marker of alcohol abuse : a critical review of the literature 2001-2005 / J Chromatogr B Analyt Technol Biom
Dawson DA / 2005 / Quantifying the risks associated with exceeding recommended drinking limits / Alcohol Clin Exp Res 29 : 902 ~ 908
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