지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 398 - 405 (8page)
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초록· 키워드
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Background: Cigarette smoking causes cardiovascular disease and activates markers of endothelial dysfunction or injury.
We investigated the nailfold capillary blood velocity (NCV) in cigarette smokers compared to non-smokers.
Methods: Forty-eight men (eighteen non-smokers and thirty smokers) were recruited. We measured NCV using nailfold capillary microscopy and exhaled carbon monoxide (ECO) concentration three times (before smoking; NCV0min and ECO0min, and after smoking; NCV5min, ECO5min, NCV30min, and ECO30min), in a condition of fasting in the case of smokers.
In non-smokers, the same measurements were taken without smoking. Additionally, personal cigarette smoking and alcohol drinking history were acquired by a self-administrated questionnaire.
Results: Mean age, waist circumference, ECO0min, ECO5min, and ECO30min was higher and NCV5min and NCV30min were significantly lower in smokers compared to non-smokers. Total smoking years were negatively correlated with NCV5min.
Average pack of the daily smoking, total pack-years, as well as total smoking years were also negatively correlated with NCV30min by regression analysis. After adjustment of significantly different variables, NCV30min was significantly lower in smokers. In the subgroup analysis, the interleukin-6 level was significantly increased in subjects with a long period of cigarette smoking compared with non-smokers.
Conclusion: Reduction of NCV in smokers is associated with personal smoking history, not with body composition or certain oxidative stress markers.
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참고문헌 (24)
참고문헌 신청
Argacha JF / 2008 / Acute effects of passive smoking on peripheral vascular function / Hypertension 51 : 1506 ~ 1511
Bazzano LA / 2003 / Relationship between cigarette smoking and novel risk factors for cardiovascular disease in the United States / Ann Intern Med 138 : 891 ~ 897
Berenson GS / 1998 / Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: the Bogalusa Heart Study / N Engl J Med 338 :
Bermudez EA / 2002 / Relation between markers of systemic vascular inflammation and smoking in women / Am J Cardiol 89 : 1117 ~ 1119
Blockmans D / 1996 / Predictive value of nailfold capillaroscopy in the diagnosis of connective tissue diseases / Clin Rheumatol 15 : 148 ~ 153
Bazzano LA / 2003 / Relationship between cigarette smoking and novel risk factors for cardiovascular disease in the United States / Ann Intern Med 138 : 891 ~ 897
Berenson GS / 1998 / Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults: the Bogalusa Heart Study / N Engl J Med 338 :
Bermudez EA / 2002 / Relation between markers of systemic vascular inflammation and smoking in women / Am J Cardiol 89 : 1117 ~ 1119
Blockmans D / 1996 / Predictive value of nailfold capillaroscopy in the diagnosis of connective tissue diseases / Clin Rheumatol 15 : 148 ~ 153
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