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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 105 - 110 (6page)
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초록· 키워드
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Schizophrenia is a complex neuropsychiatric disorder with both neurochemical and neurodevelopmental com-ponents in the pathogenesis. Growing pieces of evidence indicate that schizophrenia has pathological components that can be attributable to the abnormalities of mitochondrial function, which is supported by the recent finding suggesting mitochondrial roles for Disrupted-in-Schizophrenia 1 (DISC1). In this minireview, we briefly summarize the current un-derstanding of the molecular links between mitochondrial dysfunctions and the pathogenesis of schizophrenia, covering recent findings from human genetics, functional genomics, proteomics, and molecular and cell biological approaches.
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참고문헌 (64)
참고문헌 신청
Iwazaki, T. / 2008 / Protein expression profile in the amygdala of rats with methamphetamine- induced behavioral sensitization / Neurosci. Lett 435:113~119
Ji, B. / 2009 / A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications / J. Proteome Res 8:3633~3641
Karry, R. / 2004 / Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study / Biol. Psychiatry 55:676~684
Klushnik, T. P. / 1991 / Intracellular alterations of the creatine kinase isoforms in brains of schizophrenic patients / Mol. Chem. Neuropathol 15:271~280
Kolomeets, N. S. / 1997 / Synaptic contacts in schizophrenia: study with immunocytochemical identification of dopaminergic neurons / Zh. Nevrol. Psikhiatr. Im. S S Korsakova 97:39~43
Ji, B. / 2009 / A comparative proteomics analysis of rat mitochondria from the cerebral cortex and hippocampus in response to antipsychotic medications / J. Proteome Res 8:3633~3641
Karry, R. / 2004 / Mitochondrial complex I subunits expression is altered in schizophrenia: a postmortem study / Biol. Psychiatry 55:676~684
Klushnik, T. P. / 1991 / Intracellular alterations of the creatine kinase isoforms in brains of schizophrenic patients / Mol. Chem. Neuropathol 15:271~280
Kolomeets, N. S. / 1997 / Synaptic contacts in schizophrenia: study with immunocytochemical identification of dopaminergic neurons / Zh. Nevrol. Psikhiatr. Im. S S Korsakova 97:39~43
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