지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 360 - 366 (7page)
이용수
이 논문의 연구 히스토리 (2)
- 이 논문의 후속연구가 궁금하신가요?
- 연관 학술논문 또는 학술발표를 통해 보다 발전된 연구결과를 확인하실 수 있습니다.
- 이 논문의 연구 히스토리 확인하기
초록· 키워드
오류제보하기
Colorectal cancer (CRC), the third most common cancer worldwide, also has the highest rate of cancer-related morbidity and mortality. WNT signaling is initiated by binding of WNT to various receptors, including frizzleds (FZDs), and plays a critical role in CRC and other tumor development by regulating proliferation, differentiation, migration, apoptosis, and polarity. Among the members of the FZD family, FZD6 is broadly expressed in various tissues, and its overexpression has been reported in several cancers, suggesting an important role in cancer development. In this study, we investigated the expression of FZD6 in patients with CRC and found it to be increased in tumors, as compared to paired adjacent non-tumor tissues. Additionally, we found that FZD6 expression was negatively regulated by miR199a5p in CRC cells. These results suggest that overexpression of FZD6, mediated by reduced expression of miR-199a-5p, may play an important role in the development of CRC.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
[학술지(정기간행물
Atkin WS / 2010 / Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial / Lancet 375 : 1624 ~ 1633
Bengochea A / 2008 / Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma / Br J Cancer 99 : 143 ~ 150
Cantilena S / 2011 / Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas / Oncotarget 2 : 976 ~ 983
Chen Z / 2013 / MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/ beta-catenin pathway in hepatocellular carcinoma cells / Cell Signal 25 : 2693 ~ 270
Atkin WS / 2010 / Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial / Lancet 375 : 1624 ~ 1633
Bengochea A / 2008 / Common dysregulation of Wnt/Frizzled receptor elements in human hepatocellular carcinoma / Br J Cancer 99 : 143 ~ 150
Cantilena S / 2011 / Frizzled receptor 6 marks rare, highly tumourigenic stem-like cells in mouse and human neuroblastomas / Oncotarget 2 : 976 ~ 983
Chen Z / 2013 / MiR-27a modulates the MDR1/P-glycoprotein expression by inhibiting FZD7/ beta-catenin pathway in hepatocellular carcinoma cells / Cell Signal 25 : 2693 ~ 270
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis
Experimental and Molecular Medicine
2019 .01
-
Downregulated microRNAs in the colorectal cancer: diagnostic and therapeutic perspectives
BMB Reports
2018 .01
-
MicroRNAs: promising biomarkers for diagnosis and therapeutic targets in human colorectal cancer metastasis
BMB Reports
2015 .01
-
Quality Management of Radionuclide Activity Meter using Ge-68/Ga-68 Rod Sources
한국방사선학회 논문지
2018 .01
-
고속반도체 메모리를 위한 DBI(Data Bus Inversion)를 이용한 저비용 CRC(Cyclic Redundancy Check)방식
전기전자학회논문지
2015 .09
-
MiR-34a and miR-34b/c have distinct effects on the suppression of lung adenocarcinomas
Experimental and Molecular Medicine
2019 .01
-
낮은 복잡도를 갖는 CRC 연접 극 부호 기법
한국통신학회 학술대회논문집
2018 .01
-
Accelerated SCC Testing of Stainless Steels According to Corrosion Resistance Classes
Corrosion Science and Technology
2015 .01
-
A Median Filter for error detection Using modified pixel with CRC code
한국통신학회 학술대회논문집
2017 .06
-
Sur8 mediates tumorigenesis and metastasis in colorectal cancer
Experimental and Molecular Medicine
2016 .01
-
ANT2 shRNA downregulates miR-19a and miR-96 through the PI3K/Akt pathway and suppresses tumor growth in hepatocellular carcinoma cells
Experimental and Molecular Medicine
2016 .01
-
Therapeutic inhibition of SGK1 suppresses colorectal cancer
Experimental and Molecular Medicine
2017 .01
-
CMTM6 mediates the Warburg effect and promotes the liver metastasis of colorectal cancer
Experimental and Molecular Medicine
2024 .09
-
MiR-34a, miR-21 and miR-23a as potential biomarkers for coronary artery disease: a pilot microarray study and confirmation in a 32 patient cohort
Experimental and Molecular Medicine
2015 .01
-
Using DSP Algorithms for CRC in a CAN Controller
IEIE Transactions on Smart Processing & Computing
2016 .02
-
극부호의 오류마루를 낮추기 위한 CRC 연접 극 부호화 기술 소개
한국통신학회 학술대회논문집
2021 .06
-
miR-30c regulates proliferation, apoptosis and differentiation via the Shh signaling pathway in P19 cells
Experimental and Molecular Medicine
2016 .01
-
오류 위치 선별 및 오류 검출 능력 향상을 위한 계층적 CRC 전송 기법
한국통신학회 학술대회논문집
2020 .11
-
부호 컴퓨팅 환경에서의 CRC 를 연접한 극 부호의 적용
한국통신학회 학술대회논문집
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0