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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 655 - 667 (13page)
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Lineage tracing is a widely used method for understanding cellular dynamics in multicellular organisms during processes such as development, adult tissue maintenance, injury repair and tumorigenesis. Advances in tracing or tracking methods, from light microscopy-based live cell tracking to fluorescent label- tracing with two-photon microscopy, together with emerging tissue clearing strategies and intravital imaging approaches have enabled scientists to decipher adult stem and progenitor cell properties in various tissues and in a wide variety of biological processes. Although technical advances have enabled time-controlled genetic labeling and simultaneous live imaging, a number of obstacles still need to be overcome. In this review, we aim to provide an in-depth description of the traditional use of lineage tracing as well as current strategies and upcoming new methods of labeling and imaging.
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등록된 정보가 없습니다.
참고문헌 (132)
참고문헌 신청
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Cai D / 2013 / Improved tools for the Brainbow toolbox / Nat Methods 10:540~547
Snippert HJ / 2010 / Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells / Cell 143:134~144
Livet J / 2007 / Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system / Nature 450:56~62
Barker N / 2007 / Identification of stem cells in small intestine and colon by marker gene Lgr5 / Nature 449:1003~1007
Cai D / 2013 / Improved tools for the Brainbow toolbox / Nat Methods 10:540~547
Snippert HJ / 2010 / Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells / Cell 143:134~144
Livet J / 2007 / Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system / Nature 450:56~62
Barker N / 2007 / Identification of stem cells in small intestine and colon by marker gene Lgr5 / Nature 449:1003~1007
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