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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국인체미용예술학회 한국인체미용예술학회지 한국인체미용예술학회지 제18권 제1호
발행연도
2017.1
수록면
91 - 103 (13page)

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This study comparatively reviewed the antioxidant, antiinflammatory and anti-microbial effects of Sophora flavescens extracts. As a results of DPPH free radical, ethanol and hydrothermal extracts were 60.01% and 31.77%, respectively, at 500 μg/mL. Therefore, the former was higher in scavenging activity in a dependent fashion. Total polyphenol and flavonoid contents of the ethanol extract were 71.84 ±14.95 and 42.32 ± 1.05 μg/mL, respectively, while the hydrothermal extract was 61.20 ±2.35 and 35.80 ±4.79 μg/mL, respectively. Toxicity of ethanol extracts on HaCaT cells, no cytotoxicity was found at 10 μg/mL. In addition, concentration-dependent protective effects were verified for the oxidative stress caused by H2O2. Antimicrobial activity of ethanol extracts against skin flora such as Staphylococcus epidermidis, Staphylococcus aureus and Propionibacterium acnes were observed. a clear zone was observed in the ethanol strain. In Malassezia furfur, in contrast, antimicrobial inhibitory activity was detected in hydrothermal extracts as well. The said results show that the ethanol extract is greater than the hydrothermal extract in terms of antimicrobial, anti-inflammatory and antioxidant activities.

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