지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Atrial fi brillation (AF) and patent foramen ovale (PFO) are established sources of cardioembolism. We investigated differences in stroke outcome and patterns between PFO and AF. Methods: We performed a retrospective review of the medical records and brain MR images of patients with AF or PFO from the prospective acute stroke and transient ischemic attack registry. Infarct pattern and volume on diffusion-weighted imaging, and the national institutes of health stroke scale (NIHSS)on admission were compared between patients with AF and PFO. Results: From June 2005 to July 2008, a total of 289 subjects were enrolled (AF group, n=156; PFO group, n=133). Infarct pattern analyzed with MR images revealed that multiple vascular territorial infarction was more prevalent in AF group than in PFO group (26.9% vs. 8.3%, P <0.01). A probable cardiac embolism,radiologically defi ned as territorial infarction without symptomatic steno-occlusion of the corresponding artery, was more frequently documented in AF group than in PFO group (71.8% vs. 41.4%, P <0.01) The infarct volume of PFO was smaller than that of AF. Compared to AF, PFO was associated with the mild neurologic defi cit (NIHSS≤3) after adjusting age, sex and previous stroke history. Conclusion: These results suggested that AF and PFO had different characteristics such as infarct patterns and initial clinical severity although both are classifi ed as cardioembolism.
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참고문헌 (20)
참고문헌 신청
Adams HP Jr / 1993 / Classifi cation of subtype of acute ischemic stroke. Defi nitions for use in a multicenter clinical trial. Toast. Trial of org 10172 in Acute Stroke Tre
Adams HP Jr. / 2004 / Patent foramen ovale: Paradoxical embolism and paradoxical data / Mayo Clin Proc 79 : 15 ~ 20
Cohen A / 1997 / Aortic plaque morphology and vascular events: A follow-up study in patients with ischemic stroke. FAPS investigators. French study of aortic plaques in stro
Desai AJ / 2006 / Patent foramen ovale and cerebrovascular diseases / Nat Clin Pract Cardiovasc Med 6 : 446 ~ 455
Han SW / 2007 / Frequency and signifi cance of cardiac sources of embolism in the toast classifi - cation / Cerebrovasc Dis 24 : 463 ~ 468
Adams HP Jr. / 2004 / Patent foramen ovale: Paradoxical embolism and paradoxical data / Mayo Clin Proc 79 : 15 ~ 20
Cohen A / 1997 / Aortic plaque morphology and vascular events: A follow-up study in patients with ischemic stroke. FAPS investigators. French study of aortic plaques in stro
Desai AJ / 2006 / Patent foramen ovale and cerebrovascular diseases / Nat Clin Pract Cardiovasc Med 6 : 446 ~ 455
Han SW / 2007 / Frequency and signifi cance of cardiac sources of embolism in the toast classifi - cation / Cerebrovasc Dis 24 : 463 ~ 468
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