지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background : Ischemic stroke and coronary artery disease share the similar pathologic mechanisms. Troponin-I is a specific marker for ischemic heart injury. Previous studies suggested that Troponin-I could predict the clinical outcome of ischemic stroke. In this study, we investigated the clinical significance and prognostic value of plasma level of Troponin-I in patients with acute ischemic stroke.
Methods : Eighty-five patients with acute ischemic stroke were included in this study. Plasma Troponin-I level was measured within 24 hrs after stroke onset. We evaluated the clinical characteristics and outcome of the patients wiin acute ischemic stroke with the increased plasma concentration of Troponin-I.
Results : Fourteen patient had Troponin-I values at 0.5mg/L or higher, indicating the presence of myocardial injury. Among the 14 patients, 7 patients had large artery atherosclerotic infarction (50%), 2 patients cardioembolism (14%), 4 patients undetermined type (29%) and 1 patient had small vessel disease (7%). Patients with detectable Troponin-I level more often had abnormal values of C-reactive protein and lower functional and neurological scores at admission than those without. Also, patients with increased Troponin-I level had a tendency for poor clinical outcome.
Conclusions : These results suggest that the increased level of Troponin-I in patients with acute ischemic stroke may predict the poor outcome.
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