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Early Life Factors Influencing the Risk of Obesity
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논문 기본 정보

Type
Academic journal
Author
Journal
The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제18권 제4호 KCI Accredited Journals
Published
2015.1
Pages
217 - 223 (7page)

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Early Life Factors Influencing the Risk of Obesity
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The obesity epidemic is a worldwide problem. Factors predisposing to obesity include genetics, race, socioeconomic conditions, birth by cesarean section, and perinatal antibiotic use. High protein (HP) content in infant formulas has been identified as a potential culprit predisposing to rapid weight gain in the first few months of life and leading to later obesity. In a large multicountry study the effects of lower protein (LP) formula (1.77 and 2.2 g protein/100 kcal, before and after the 5th month, respectively) were compared to those of higher protein (2.9 and 4.4 g protein/100 kcal, respectively). Results indicated that at 24 months, the weight-for-length z score of infants in the LP formula group was 0.20 (0.06, 0.34) lower than that of the HP group and was similar to that of the breastfed reference group. The authors concluded that a HP content of infant formula is associated with higher weight in the first 2 years of life but has no effect on length. LP intake in infancy might diminish the later risk of overweight and obesity. At 6 years of age HP children had a significantly higher body mass index (by 0.51; 95% confidence interval [CI], 0.13-0.90; p=0.009) and a 2.43 (95% CI, 1.12-5.27; p=0.024) fold greater risk of becoming obese than those who received the LP. In conclusion, several factors may influence development of metabolic syndrome and obesity. Breastfeeding should always be encouraged. An overall reduction of protein intake in formula non breastfed infants seems to be an additional way to prevent obesity.
#Obesity #Infant formula #Low protein formula #Cesarean section

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References (36)

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Volz VR / 1983 / Growth and plasma amino acid concentrations in term infants fed either whey-predominant formula or human milk / J Pediatr 102:27~31 google schola Harrison GG / 1987 / Growth and adiposity of term infants fed whey-predominant or casein-predominant formulas or human milk / J Pediatr Gastroenterol Nutr 6:739~747 google schola Köhler L / 1984 / Food intake and growth of infants between six and twenty-six weeks of age on breast milk, cow's milk formula, or soy formula / Acta Paediatr Scand 73:40~48 google schola Koletzko B / 2005 / Early nutrition and its later consequences:new opportunities / Adv Exp Med Biol 569:1~12 google schola Koletzko B / 2009 / Lower protein in infant formula is associated with lower weight up to age 2 y: a randomized clinical trial / Am J Clin Nutr 89:1836~1845 google schola

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