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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Cerebral microbleeds (CMBs) are tiny, round dark-signal lesions that are most often detected on gradient-echo MR images. CMBs consist of extravasations of blood components through fragile microvascular walls characterized by lipohyalinosis and surrounding macrophages. The prevalence of CMBs in elderly subjects with no history of cerebrovascular disease is around 5%, but is much higher in patients with ischemic or hemorrhagic stroke. Development of CMBs is closely related to various vascular risk factors; in particular, lobar CMBs are thought to be associated with cerebral amyloid angiopathy. The presence of CMBs has been hypothesized to reflect cerebral-hemorrhage-prone status in patients with hypertension or amyloid microangiopathy. Stroke survivors with CMBs have been consistently found to have an elevated risk of subsequent hemorrhagic stroke or an antithrombotic-related hemorrhagic complication, although studies have failed to establish a link between CMBs and hemorrhagic transformation after thrombolytic treatment. A large prospective study is required to clarify the clinical significance of CMBs and their utility in a decision-making index.
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참고문헌 (24)
참고문헌 신청
Atlas SW / 1988 / Intracranial hemorrhage: gradient-echo MR imaging at 1.5 T. Comparison with spin-echo imaging and clinical applications / Radiology 168 : 803 ~ 807
Ayaz M / 2010 / Imaging cerebral microbleeds using susceptibility weighted imaging: one step toward detecting vascular dementia / J Magn Reson Imaging 31 : 142 ~ 148
Cordonnier C / 2007 / Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting / Brain 130 : 1988 ~ 2003
Fan YH / 2003 / Cerebral microbleeds as a risk factor for subsequent intracerebral hemorrhages among patients with acute ischemic stroke / Stroke 34 : 2459 ~ 2462
Fazekas F / 1999 / Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of
Ayaz M / 2010 / Imaging cerebral microbleeds using susceptibility weighted imaging: one step toward detecting vascular dementia / J Magn Reson Imaging 31 : 142 ~ 148
Cordonnier C / 2007 / Spontaneous brain microbleeds: systematic review, subgroup analyses and standards for study design and reporting / Brain 130 : 1988 ~ 2003
Fan YH / 2003 / Cerebral microbleeds as a risk factor for subsequent intracerebral hemorrhages among patients with acute ischemic stroke / Stroke 34 : 2459 ~ 2462
Fazekas F / 1999 / Histopathologic analysis of foci of signal loss on gradient-echo T2*-weighted MR images in patients with spontaneous intracerebral hemorrhage: evidence of
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