지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제15권 제2호
- 발행연도
- 2012.1
- 수록면
- 111 - 116 (6page)
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초록· 키워드
오류제보하기
Toxic hepatitis is a rare but devastating disease in children. Herbs are widely used in oriental medicine to treat various symptoms in Korea, however, several herbs have been reported to induce liver injury. We report a case of toxic hepatitis induced by Hovenia dulcis in a 3-year-old boy. He complained of nausea, abdominal discomfort, and jaundice. The patient had consumed water boiled with hovenia dulcis for about 1 year prior to presentation. A diagnosis of toxic hepatitis was made based on his history, laboratory data, viral markers, ultrasonography, and biopsied liver tissue. We administered supportive management for acute fulminant hepatitis but his symptoms and liver function progressed. He was transferred to another hospital for further evaluation and consideration for liver transplantation. Because acute liver failure due to herbs or dietary supplement taken for a long time is often fetal, it is important to make early diagnosis and stop taking the drug as soon as drug induced liver injury is suspected.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Benchou C / 1990 / Criteria of drug-induced liver disorders. Report of an international meeting / J Hepatol 11 : 272 ~ 276
Berardinis V / 2000 / Human microsomal epoxide hydrolase is the target of germander-induced autoantibodies on the surface of human hepatocytes / Mol Pharmacol 58 : 542 ~ 551
Bissell DM / 2001 / Drug-induced liver injury:mechanisms and test systems / Hepatology 33 : 1009 ~ 1013
Fang HL / 2007 / Treatment of chronic liver injuries in mice by oral administration of ethanolic extract of the fruit of Hovenia dulcis / Am J Chin Med 35 : 693 ~ 703
Fontana RJ / 2009 / Drug-induced liver injury network (DILIN) prospective study: rationale, design and conduct / Drug Safety 32 : 55 ~ 68
Berardinis V / 2000 / Human microsomal epoxide hydrolase is the target of germander-induced autoantibodies on the surface of human hepatocytes / Mol Pharmacol 58 : 542 ~ 551
Bissell DM / 2001 / Drug-induced liver injury:mechanisms and test systems / Hepatology 33 : 1009 ~ 1013
Fang HL / 2007 / Treatment of chronic liver injuries in mice by oral administration of ethanolic extract of the fruit of Hovenia dulcis / Am J Chin Med 35 : 693 ~ 703
Fontana RJ / 2009 / Drug-induced liver injury network (DILIN) prospective study: rationale, design and conduct / Drug Safety 32 : 55 ~ 68
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