지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: In recent studies, by utilizing single photon emission computed tomography (SPECT) and magnetic resonance angiography (MRA), anatomical and functional evaluation became possible. Although MRA is increasingly being used to evaluate vascular status, conventional angiography is still gold standard for investigating anatomical structures. We studied the correlation between internal carotid artery (ICA) stenosis, patterns of collateral pathway, and cerebrovascular reserve using transfemoral cerebral angiography (TFCA) and SPECT. Methods: We studied 54 patients with symptomatic ICA stenosis who were visit to our hospital between Sep 2009 and May 2011. Forms of collateral pathway were classified into primary and secondary pathway group. Severity of ICA stenosis was divided into 4 stages. Vascular reserve on SPECT was classified into favorable and poor groups. Results: As a result of TFCA, collateral pathways were observed in 44 of 54 patients. Collateral flow via anterior communicating artery (AcoA) pattern occupied the highest proportion and other major patterns were collaterals via posterior cerebral artery-middle cerebral artery (PCA-MCA) and via posterior communicating artery (PCoA) pattern. Twentyeight patients were primary pathway group and 16 patients were secondary pathway group. In both groups, most patients had moderate or severe ICA stenosis. As a result of SPECT, favorable vascular reserves were observed in 17 of 54 patients. Most of them had mild ICA stenosis and/or primary collateral pathway. Contrarily, most of secondary pathway group had poor vascular reserve even if their ICA stenosis severity was mild. Conclusion: In patients with symptomatic ICA stenosis with collateral pathways, rate of primary collateral pathways was higher than secondary collateral pathways. Secondary collateral pathways had insufficient compensatory effect about reduced cerebral blood perfusion.
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참고문헌 (21)
참고문헌 신청
Alexandrov AV / 1996 / Simple visual analysis of brain perfusion on HMPAO SPECT predicts early outcome in acute stroke / Stroke 27 : 1537 ~ 1542
Del Sette M / 2000 / Internal borderzone infarction: a marker for severe stenosis in patients with symptomatic internal carotid artery disease / Stroke 31 : 631 ~ 636
Hedera P / 1998 / Stroke risk factors and development of collateral flow in carotid occlusive disease / Acta Neurol Scand 98 : 182 ~ 186
Hendrikse J / 2001 / Collateral ability of the circle of Willis in patients with unilateral internal carotid artery occlusion: border zone infarcts and clinical symptoms / S
Hendrikse J / 2003 / Effect of carotid endarterectomy on primary collateral blood flow in patients with severe carotid artery lesions / Stroke 34 : 1650 ~ 1654
Del Sette M / 2000 / Internal borderzone infarction: a marker for severe stenosis in patients with symptomatic internal carotid artery disease / Stroke 31 : 631 ~ 636
Hedera P / 1998 / Stroke risk factors and development of collateral flow in carotid occlusive disease / Acta Neurol Scand 98 : 182 ~ 186
Hendrikse J / 2001 / Collateral ability of the circle of Willis in patients with unilateral internal carotid artery occlusion: border zone infarcts and clinical symptoms / S
Hendrikse J / 2003 / Effect of carotid endarterectomy on primary collateral blood flow in patients with severe carotid artery lesions / Stroke 34 : 1650 ~ 1654
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