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Intracranial large artery disease (ILAD) is the major cause of stroke worldwide. With the application of recently introduced diagnostic techniques, the prevalence of non-atherosclerotic ILAD is expected to increase. Herein, we reviewed recent reports and summarized progress in the diagnosis and clinical impact of differentiation between ILAD of atherosclerotic and non-atherosclerotic origin. Our review of the literature suggests that more careful consideration of non-atherosclerotic causes and the application of appropriate diagnostic techniques in patients with ILAD may not only provide better results in the treatment of patients, but it may also lead to more successful clinical trials for the treatment of intracranial atherosclerosis.
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참고문헌 (87)
참고문헌 신청
Chimowitz MI / 2005 / Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis / N Engl J Med 352:1305~1316
Chimowitz MI / 2011 / Stenting versus aggressive medical therapy for intracranial arterial stenosis / N Engl J Med 365:993~1003
Leung TW / 2015 / Evolution of intracranial atherosclerotic disease under modern medical therapy / Ann Neurol 77:478~486
Wong KS / 2002 / Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis: a diffusion-weighted imaging and microemboli monitoring study / Ann Neurol 52:74~81
Ryoo S / 2015 / Differential vascular pathophysiologic types of intracranial atherosclerotic stroke: a high-resolution wall magnetic resonance imaging study / Stroke 46:2815~2821
Chimowitz MI / 2011 / Stenting versus aggressive medical therapy for intracranial arterial stenosis / N Engl J Med 365:993~1003
Leung TW / 2015 / Evolution of intracranial atherosclerotic disease under modern medical therapy / Ann Neurol 77:478~486
Wong KS / 2002 / Mechanisms of acute cerebral infarctions in patients with middle cerebral artery stenosis: a diffusion-weighted imaging and microemboli monitoring study / Ann Neurol 52:74~81
Ryoo S / 2015 / Differential vascular pathophysiologic types of intracranial atherosclerotic stroke: a high-resolution wall magnetic resonance imaging study / Stroke 46:2815~2821
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