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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아내분비학회 Annals of Pediatirc Endocrinology & Metabolism Annals of Pediatirc Endocrinology & Metabolism 제22권 제4호
- 발행연도
- 2017.1
- 수록면
- 219 - 225 (7page)
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초록· 키워드
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The prevalence of obesity around the world has increased sharply. Strong evidence has emerged over the last decades that human exposure to numerous endocrine disrupting chemicals (EDCs) is the cause of obesity and obesity-related metabolic diseases. Many EDCs are manmade chemicals that are released into the environment. EDCs are exogenous compounds that interfere with hormonal regulation and normal endocrine systems, thereby affecting the health of animals and humans. The number of chemicals belonging to EDCs is increasing and some of them are very stable; they persist in the environment (persistent organic pollutants). Although they are banned, their concentrations have been continuously increasing over time. This review gives a brief introduction to common EDCs, and evidence of harmful effects of EDCs on obesity-related diseases; we focus in particular on EDCs’ role in causing mitochondrial dysfunction.
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등록된 정보가 없습니다.
참고문헌 (49)
참고문헌 신청
Morino K / 2005 / Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents / J Clin Invest 115:3587~3593
Park KS / 2008 / A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians / Diabetologia 51:602~608
Fuku N / 2007 / Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians / Am J Hum Genet 80:407~415
Solomon KR / 2013 / Ecological risk assessment of atrazine in North American surface waters / Environ Toxicol Chem 32:10~11
Lim S / 2009 / Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance / PLoS One 4:e5186
Park KS / 2008 / A mitochondrial DNA variant at position 16189 is associated with type 2 diabetes mellitus in Asians / Diabetologia 51:602~608
Fuku N / 2007 / Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians / Am J Hum Genet 80:407~415
Solomon KR / 2013 / Ecological risk assessment of atrazine in North American surface waters / Environ Toxicol Chem 32:10~11
Lim S / 2009 / Chronic exposure to the herbicide, atrazine, causes mitochondrial dysfunction and insulin resistance / PLoS One 4:e5186
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