지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Intracranial atherosclerosis (ICAS) is a major cause of stroke worldwide and is more common in Asians than Caucasians. The study results from the East and West are generally similar, but notable differences exist. For example, studies from the East have reported that ICAS is associated with young age, whereas ICAS seems to be associated with old age in the West. Studies from the East have strongly suggested that mild ICAS associated with branch occlusion is one of the main causes of single subcortical infarction, whereas this aspect has not been considered in stroke classification systems developed in the West. While clopidogrel is commonly used in patients with large artery disease in the West, cilostazol has been more extensively studied and commonly used in ICAS patients in the East. A randomized controlled study from the West reported negative results regarding the efficacy of stenting in ICAS patients due largely to a relatively high rate of periprocedural adverse events, whereas research papers from the East have reported a relatively lower rate of complications. Studies to narrow these East-West gaps should be performed, including risk factor studies using homogenous ethnic populations, studies investigating appropriate classification systems, drug trials in different ethnic populations, and rigorous high standard randomized controlled studies on the efficacy of stenting in Eastern populations.
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등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Bang OY. / 2005 / Association of the metabolic syndrome with intracranial atherosclerotic stroke / Neurology 65 : 296 ~ 298
Bang OY. / 2009 / Impact of metabolic syndrome on distribution of cervicocephalic atherosclerosis : data from a diverse race-ethnic group / J Neurol Sci 284 : 40 ~ 45
Caplan LR. / 1986 / Race, sex and occlusive cerebrovascular disease : a review / Stroke 17 : 648 ~ 655
Chandalia M. / 1999 / Relationship between generalized and upper body obesity to insulin resistance in Asian Indian men / J Clin Endocrinol Metab 84 : 2329 ~ 2335
D’Armiento FP. / 2001 / Age-related effects on atherogenesis and scavenger enzymes of intracranial and extracranial arteries in men without classic risk factors for atherosc
Bang OY. / 2009 / Impact of metabolic syndrome on distribution of cervicocephalic atherosclerosis : data from a diverse race-ethnic group / J Neurol Sci 284 : 40 ~ 45
Caplan LR. / 1986 / Race, sex and occlusive cerebrovascular disease : a review / Stroke 17 : 648 ~ 655
Chandalia M. / 1999 / Relationship between generalized and upper body obesity to insulin resistance in Asian Indian men / J Clin Endocrinol Metab 84 : 2329 ~ 2335
D’Armiento FP. / 2001 / Age-related effects on atherogenesis and scavenger enzymes of intracranial and extracranial arteries in men without classic risk factors for atherosc
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