지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 355 - 371 (17page)
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초록· 키워드
오류제보하기
Objective: This study was performed to develop a program for predicting individual cancer risk and to validate its discrimination power between case and control groups. Methods: The author used the five databases for searching journals about risk factors of six major cancers in Koreans: stomach, liver, colorectal, breast, uterine cervix and lung cancer. The risk models were selected from journals presenting a multivariate linear logistic regression analysis. The baseline hazards which had no risk factors were calculated, and a cancer risk assessment program was developed using relative risks based on risk factors' combination and baseline hazards. Case-control study was performed for five years to validate the program. Results: The discrimination power between case and control was 0.827 in stomach cancer, 0.949 in liver cancer, 0.594 in colorectal cancer, 0.587 in breast cancer, 0.708 in uterine cervix cancer and 0.663 in lung cancer. The estimated cancer probabilities were higher in all case groups compared to the control groups. Conclusion: The developed program is considered to be a valid tool for estimating probabilities of cancer development in Koreans. It is expected to be useful for the assessment of individual cancer risks, the selection of screening tools and preventive options for risk reduction.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Bae JI / 2001 / A hospital-based case-control study on the risk factors of stomach cancer / J Korean Acad Fam Med 22 : 539 ~ 547
Chang WK / 2001 / Association between Helicobacter pylori infection and the risk of gastric cancer in the Korean population: prospective case-controlled study / J Gastroente
Cheong JY / 2001 / Establishment of individual prediction model according to risk factors for development of hepatocellular carcinoma in Korea: Establishment of individual p
Choi SY / 1998 / Effect of Non-dietary Factors in the Etiology of Stomach Cancer / Korean J Epidemiol 20 : 102 ~ 112
Colditz GA / 2000 / Harvard report on cancer prevention volume 4: Harvard Cancer Risk Index. Risk Index Working Group, Harvard Center for Cancer Prevention / Cancer Causes C
Chang WK / 2001 / Association between Helicobacter pylori infection and the risk of gastric cancer in the Korean population: prospective case-controlled study / J Gastroente
Cheong JY / 2001 / Establishment of individual prediction model according to risk factors for development of hepatocellular carcinoma in Korea: Establishment of individual p
Choi SY / 1998 / Effect of Non-dietary Factors in the Etiology of Stomach Cancer / Korean J Epidemiol 20 : 102 ~ 112
Colditz GA / 2000 / Harvard report on cancer prevention volume 4: Harvard Cancer Risk Index. Risk Index Working Group, Harvard Center for Cancer Prevention / Cancer Causes C
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