지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 356 - 370 (15page)
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초록· 키워드
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Barrett’s esophagus (BE) is the only known precursor toesophageal adenocarcinoma (EAC), whose incidence hasincreased sharply in the last 4 decades. The annual conversionrate of BE to cancer is significant, but small. The identificationof patients at a higher risk of cancer therefore poses aclinical conundrum. Currently, endoscopic surveillance is recommendedin BE patients, with the aim of diagnosing eitherdysplasia or cancer at early stages, both of which are curablewith minimally invasive endoscopic techniques. There is alarge variation in clinical practice for endoscopic surveillance,and dysplasia as a marker of increased risk is affected bysampling error and high interobserver variability. Screeningprograms have not yet been formally accepted, mainly dueto the economic burden that would be generated by uppergastrointestinal endoscopy. Screening programs have not yetbeen formally accepted, mainly due to the economic burdenthat would be generated by widespread indication to uppergastrointestinal endoscopy. In fact, it is currently difficult toformulate an accurate algorithm to confidently target thepopulation at risk, based on the known clinical risk factorsfor BE and EAC. This review will focus on the clinical andmolecular factors that are involved in the development of BEand its conversion to cancer and on how increased knowledgein these areas can improve the clinical management ofthe disease
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참고문헌 (24)
참고문헌 신청
American Gastroenterological Association / 2011 / American Gastroenterological Association medical position statement on the management of Barrett’s esophagus / Gastroentero
Anderson LA / 2007 / Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma: results from the FINBAR study / World J Gastroenterol 13 : 1585 ~ 1594
Bhat S / 2011 / Risk of malignant progression in Barrett’s esophagus patients: results from a large population-based study / J Natl Cancer Inst 103 : 1049 ~ 1057
Cancer Research UK / / Oesophageal cancer statistics
Connor MJ / 2004 / The prevalence of Barrett’s esophagus and erosive esophagitis in patients undergoing upper endoscopy for dyspepsia in a VA population / Dig Dis Sci 49 : 9
Anderson LA / 2007 / Risk factors for Barrett’s oesophagus and oesophageal adenocarcinoma: results from the FINBAR study / World J Gastroenterol 13 : 1585 ~ 1594
Bhat S / 2011 / Risk of malignant progression in Barrett’s esophagus patients: results from a large population-based study / J Natl Cancer Inst 103 : 1049 ~ 1057
Cancer Research UK / / Oesophageal cancer statistics
Connor MJ / 2004 / The prevalence of Barrett’s esophagus and erosive esophagitis in patients undergoing upper endoscopy for dyspepsia in a VA population / Dig Dis Sci 49 : 9
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