Relationship between Psychological Factors and Quality of Life in Subtypes of Gastroesophageal Reflux Disease

오정환; 김태석; 최명규; Hyeug Lee; 전은정; 최상욱; 이철; 정인식

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자료유형: 학술저널

저자정보: 오정환 김태석 최명규 Hyeug Lee 전은정 최상욱 이철 정인식

저널정보: 거트앤리버 발행위원회 Gut and Liver Gut and Liver 제3권 제4호

발행연도: 2009.1

수록면: 259 - 265 (7page)

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Background/Aims: Quality of life (QoL) is consistently decreased in gastroesophageal reflux disease (GERD), but the relationship between QoL and psychological factors in GERD has not yet been clearly defined. The present study investigated the relationship between the psychological factors of two subtypes of GERD and QoL. Methods: A cohort of 769 participants underwent upper endoscopic evaluation in the health-promotion center of St. Paul’s Hospital. The severity of GERD symptoms, psychological factors, and QoL were analyzed using the Visual Analogue Scale, the Hospital Anxiety and Depression Scale, and the abbreviated version of the World Health Organization Quality of Life instrument, respectively. Results: Among the total of 769 participants, 153 participants were included in the exclusion criteria. Erosive reflux disease (ERD) and nonerosive reflux disease (NERD) were present in 106 (14%) and 61 (8%) of the participants, respectively, and 449 (58%) acted as controls. In each GERD group, the QoL had no correlatioion with the symptom severity. The scores for anxiety and depression were highest in the NERD group, and QoL scores were lower in both the ERD and NERD groups than in the control group. Anxiety and depression resulted in QoL scores being lower in both the ERD and NERD groups than in the nonanxiety and nondepressed groups, respectively. Conclusions: This study provides evidence that the QoL associated with the ERD and NERD subtypes may be more related to psychological factors than to symptom severity.

#Gastroesophageal reflux #Quality of life #Anxiety #Depression #Psychology

참고문헌 (24)

참고문헌 신청

Agreus L / 2001 / Natural history of gastroesophageal reflux disease and functional abdominal disorders: a population-based study / Am J Gastroenterol 96 : 2905 ~ 2914

Aina Y / 2006 / Understanding comorbidity with depression and anxiety disorders / J Am Osteopath Assoc 106 : S9 ~ 14

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Bredenoord AJ / 2006 / Determinants of perception of heartburn and regurgitation / Gut 55 : 313 ~ 318

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Jung Hwan Oh

소속기관 College of Medicine The Catholic University of Korea Seoul Korea

주요연구분야 의약학 > 임상의학 > 내과학

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