지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 275 - 286 (12page)
이용수
초록· 키워드
오류제보하기
In the present study, antioxidant activity and protective effect of extracts from Sambucus williamsii var. coreanastems (SWC) were evaluated on tert-butyl hydroperoxide (t-BHP) induced oxidative stress in human liver (Chang)cells. Antioxidant activities of the SWC extracts were determined by various radical scavenging activities, suchas DPPH, ferric reducing antioxidant power (FRAP), 2,2’-azinobis-(3-ethybenzothiazoline-6-sulfonic acid)(ABTS) radical scavenging activity and oxygen radical absorbance capacity (ORAC) assay. SWC extracts showedstrong antioxidant effect on various assay. To determine the hepatoprotective effects of SWC on t-BHP inducedoxidative damage, cell viability was measured using MTT assay. Pretreatment of SWC extracts showed increasingcell viability, decreasing ROS and restoring mitochondria membrane potential on t-BHP induced oxidative stressin Chang cells. Our findings suggest that SWC extracts may be considered a potential agent for therapeuticprotective effect from oxidative stress through its antioxidant activity.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Bartsch, H / 2006 / Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: Role of lipid peroxidation, DNA damage, and repair / Langenbeck Arch
Benzie, I. F. F. / 1999 / Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous me
Blois, M. S / 1958 / Antioxidant determination by the use of stable free radical. Nature / Nature 26 : 1198 ~ 1199
Cho, S. K. / 1994 / Analgesic and Anti-inflammatory Activity of Sambucus sieboldiana Water extract / Chung-Ang J Pharm Sci 8 : 57 ~ 65
Comelli, M.C / 2007 / Toward the definition of the mech anism of action of silymarin: Activities related to cellular protection from toxic damage induced by chemotherapy / In
Benzie, I. F. F. / 1999 / Ferric reducing/antioxidant power assay: direct measure of total antioxidant activity of biological fluids and modified version for simultaneous me
Blois, M. S / 1958 / Antioxidant determination by the use of stable free radical. Nature / Nature 26 : 1198 ~ 1199
Cho, S. K. / 1994 / Analgesic and Anti-inflammatory Activity of Sambucus sieboldiana Water extract / Chung-Ang J Pharm Sci 8 : 57 ~ 65
Comelli, M.C / 2007 / Toward the definition of the mech anism of action of silymarin: Activities related to cellular protection from toxic damage induced by chemotherapy / In
이 논문의 저자 정보
최근 본 자료
댓글(0)
0