지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 41 - 48 (8page)
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Background/Aims: As the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with hospital-acquired diarrhea (HAD). This study focused on identifying the clinical risk factors that can easily predict PMC.
Methods: The presumed HAD patients were prospectively recruited at the Hallym University Kangdong Sacred Heart Hospital.
Results: Age of 70 and older (adjusted odds ratio [OR], 1.76; 95% confidence interval [CI], 1.12 to 0.75), use of proton pump inhibitors (adjusted OR, 4.07; 95% CI, 2.512 to 6.57), use of cephalosporins (adjusted OR, 2.99; 95% CI, 1.82 to 4.94), and underlying cancer (adjusted OR, 1.72; 95% CI, 1.04 to 2.82) were independent risk factors for PMC in the multivariate logistic regression analysis. The prevalence of PMC was very low in the patients with HAD who exhibited no risk factors.
Conclusions: The risk factors for PMC in patients with HAD included cephalosporin use, proton pump inhibitor use, old age, and cancer. Considering the strongly negative predictive values of these risk factors, endoscopic evaluation can be delayed in patients with HAD without risk of developing PMC.
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참고문헌 (25)
참고문헌 신청
[학술지(정기간행물)]
Allen SJ / 2012 / A multicentre randomised controlled trial evaluating lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea in older people a
Bartlett JG / 2002 / Clinical practice. Antibiotic-associated diarrhea / N Engl J Med 346 : 334 ~ 339
Changela U / 2004 / Risk factors and mortality associated with Clostridium difficile-associated diarrhoea at a VA hospital / Int J Antimicrob Agents 24 : 562 ~ 566
Cunningham R / 2003 / Proton pump inhibitors as a risk factor for Clostridium difficile diarrhoea / J Hosp Infect 54 : 243 ~ 245
Allen SJ / 2012 / A multicentre randomised controlled trial evaluating lactobacilli and bifidobacteria in the prevention of antibiotic-associated diarrhoea in older people a
Bartlett JG / 2002 / Clinical practice. Antibiotic-associated diarrhea / N Engl J Med 346 : 334 ~ 339
Changela U / 2004 / Risk factors and mortality associated with Clostridium difficile-associated diarrhoea at a VA hospital / Int J Antimicrob Agents 24 : 562 ~ 566
Cunningham R / 2003 / Proton pump inhibitors as a risk factor for Clostridium difficile diarrhoea / J Hosp Infect 54 : 243 ~ 245
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