Metastasis of Hepatocellular Carcinoma to the Ovary: A Case Report and Review of the Literature

이재명; Kwang-Min Park; So Young Lee; Julian Choi; Dae Wook Hwang; Young Joo Lee

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자료유형: 학술저널

저자정보: 이재명 Kwang-Min Park So Young Lee Julian Choi Dae Wook Hwang Young Joo Lee

저널정보: 거트앤리버 발행위원회 Gut and Liver Gut and Liver 제5권 제4호

발행연도: 2011.1

수록면: 543 - 547 (5page)

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Metastasis of hepatocellular carcinoma (HCC) to the ovary is notably rare. We present a case of HCC metastasis to the ovary with a review of the literature, which includes only 7reported cases. A 43-year-old hepatitis B virus carrier was admitted with a right ovarian cystic mass. She had been diagnosed with HCC 2 years prior, for which she underwent transarterial chemoembolization followed by right posterior sectionectomy. Eight months after the hepatectomy, the fi rst intrahepatic recurrence was detected and treated with transarterial chemoembolization. An additional intrahepatic recurrence occurred 12 months after transarterial chemoembolization and was managed with left medial sectionectomy and intra-operative radiofrequency ablation. Over the following 3months, the patient developed elevated alpha-fetoprotein,and positron emission tomography showed a cystic mass in the right side of the pelvic cavity with focal hypermetabolic activity, which suggested a site of recurrent HCC. An exploratory laparotomy was performed, and a soft, ovoid cystic mass was identifi ed in the right ovary. There was no evidence of metastases in the liver, left ovary, or peritoneum. Because of the absence of tumor on the surface of the ovary and the lack of peritoneal seeding, the mode of metastasis was thought to be hematogenous. Therefore, a right salphingooophorectomy was performed. The pathological features showed metastatic HCC with clear resection margins. Although metastasis of HCC to the ovary is very rare, it should be suspected in a female patient with a lower abdominal mass and an elevated serum AFP level in the absence of other demonstrable metastases.

#Hepatocellular carcinoma #Metastasis #Ovary

참고문헌 (25)

참고문헌 신청

Font RL / 1998 / Hepatocellular carcinoma metastatic to the orbit / Arch Ophthalmol 116 : 942 ~ 945

Frigy AF / 1984 / Metastatic hepatocellular carcinoma of the nasal cavity / Arch Otolaryngol 110 : 624 ~ 627

Hong SS / 2003 / Extrahepatic spread of hepatocellular carcinoma: a pictorial review / Eur Radiol 13 : 874 ~ 882

Ishikura H / 1987 / Hepatoid carcinoma of the ovary: a newly described tumor / Cancer 60 : 2775 ~ 2784

Khunamornpong S / 1999 / Metastatic hepatocellular carcinoma of the ovary / Int J Gynaecol Obstet 64 : 189 ~ 191

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이재명

소속기관 거트앤리버 발행위원회

주요연구분야 의약학 > 임상의학 > 내과학

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Kwang-Min Park