지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 278 - 287 (10page)
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초록· 키워드
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Although the prevalence of chronic hepatitis B has decreased considerably in recent years due to widespread use of the hepatitis B virus (HBV) vaccine, its prevalence still remains high in adults, and this can place a significant burden on health care in areas with endemic HBV. Since the introduction of nucleos(t)ide analogues (NUCs), there has been marked improvement in the care of patients with chronic hepatitis B, resulting in increased survival. However, the emergence of drug resistance in patients treated with NUCs is a major concern. The number of multi-drug resistant patients is increasing, and many patients may not respond to the currently available drugs. In this review, we describe the current status of NUC therapy for antiviral-naïve and -resistant patients.
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참고문헌 (80)
참고문헌 신청
Yuen MF / 2011 / Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy / Hepatology 34(4 Pt 1):785~791
Marcellin P / 2003 / Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B / N Engl J Med 348:808~816
Marcellin P / 2008 / Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B / Hepatology 48:750~758
Hadziyannis SJ / 2005 / Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B / N Engl J Med 352:2673~2681
Hadziyannis SJ / 2003 / Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B / N Engl J Med 348:800~807
Marcellin P / 2003 / Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B / N Engl J Med 348:808~816
Marcellin P / 2008 / Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B / Hepatology 48:750~758
Hadziyannis SJ / 2005 / Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B / N Engl J Med 352:2673~2681
Hadziyannis SJ / 2003 / Adefovir dipivoxil for the treatment of hepatitis B e antigen-negative chronic hepatitis B / N Engl J Med 348:800~807
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