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Endoscopic ultrasound (EUS) and endoscopic retrogradecholangiopancreatography (ERCP) are essential for diagnosingand treating pancreatobiliary diseases. Single-sessionEUS and ERCP are considered to be essential in reducingthe duration of hospital stays; however, complications are aprimary concern. The aim of this study was to evaluate thesafety and efficacy of single-session EUS and ERCP. Sixtyeightpatients underwent single-session EUS and ERCP at atertiary referral center between June 2008 and December2012. We retrospectively reviewed patient data from a prospectivelymaintained EUS-ERCP database and evaluatedthe procedural characteristics and complications. Thirty-eightpatients (56%) underwent diagnostic EUS, and 30 patients(44%) underwent EUS fine-needle aspiration, which had anoverall accuracy of 100%. Sixty patients (89%) underwenttherapeutic ERCP, whereas the remaining eight procedureswere diagnostic. Thirteen patients underwent biliary stoneextraction, and 48 underwent biliary drainage. The mediantotal procedural time was 75 minutes. Complications wereobserved in seven patients (10%). Six complications werepost-ERCP pancreatitis, which were resolved using conservativemanagement. One patient developed Mallory-Weiss syndrome,which required endoscopic hemostasis. No sedationrelatedcardiopulmonary complications were observed. Single-session EUS and ERCP provided accurate diagnosisand effective management with a minimal complication rate.

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