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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2003.1
- 수록면
- 81 - 86 (6page)
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Purpose : Streptococcus pneumoniae remains a leading cause of meningitis, sepsis, pneumonia,
and otitis media in children worldwide. Emergence of drug-resistant organism has substantially
complicated the therapy of these infections. This study was conducted to determine
the clinical features and changing patterns of antibiotic-resistant rates of Streptococcus pneumoniae.
Methods : We have retrospectively examined 306 cases of culture proven patients who
were admitted to the Department of Pediatrics, Severance hospital, from the year 1991 to
year 2000. The type of culture specimen used, presence of penicillin resistance, characteristics
according to various presenting diseases and their prevailing year were also examined.
Results : The mean age of cases was 7.9 year and the ratio of male to female was 1.6 :
1. The main age group of pneumococcal infection was under 2 years(42%). Systemic infections
associated with pneumococci were sepsis(19.3%) and meningitis(9.5%), while local infections
presented as pneumonia(29.2%), otitis media(19.3%), exudative tonsillitis(13.3%), and
sinusitis(9.2%) in the order of frequency. Seasonal variation was seen in the incidence of
pneumococcal infection: high incidence of infection was seen in Spring(Mar.～Apr; 32%),
while the incidence was low during summer(Aug.～Sep.; 6%). Penicillin-resistant rate of
pneumococci was steadily on the increase since the year 1991(65%) to year 2000(84%).
Conclusion : Antibiotic-resistant pneumococci increased during the past decade. For effective
prevention of pneumococcal infections, national survey of pneumococcal infections and
expanded use of pneumococcal vaccination would be needed.
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