지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The purpose of this study was to evaluate the hair growth effect of Dansam-Samultang in C57BL/6 mice. In order to estimate its hair growth effect, we performed percutaneous application of sample on the back of six-week-old C57BL/6male mice; 150 μL a day, six days a week, for four weeks. Experimental animals were classified into four groups - control group (C, saline), positive control group (PC, minoxidil 3%), experimental 1 group (E1, Dansam-Samultang ethanol 2%),and experimental 2 group (E2, Dansam-Samultang toner 2%). Body weight, water and feed consumption were measured once a week, and macroscopic hair growth effect was observed once a week. On the second and fourth week, we took a blood sample of five mice, analyzed their blood cells, observed their skin tissues. The experiment showed no significance in water and feed consumption, body weight gain, and feed efficiency among groups; relatively high weight gain, but no statistical significance for PC group. The organ weight had no significant difference among groups. In the hematological analysis, E1 had more white blood cells, neutrophils, and monocytes, but there was no significant difference in other items among groups. Macroscopic observation showed hair growth effect in the high to low order of PC, E1, E2, and C groups. Histological observation showed a clear increase of number and depth of follicle, and dermal thickness for PC, E1and E2 groups, compared to C group. Taking all the results together, this experiment shows that Dansam-Samultang has a effective in hair growth and hair loss prevention.
목차
등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Yoo JY / 2002 / The effects Damsam-Samultang on hematopoiesis / J Kor Ori Med 23(1):145~155
Yusur AN / 2010 / The cycling hair follicle as an ideal systems biology research model / Exp Dermatol 19:707~713
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Clarkson PM / 2000 / Antioxidants: what role do they play in physical activity and health / Am J Clin Nut 72 : 637 ~ 646
Esfandiari A / 2005 / The effects of tea polyphenolic compounds on hair loss among rodents / J National Med Assoc 97 (8) : 1165 ~ 1169
Yusur AN / 2010 / The cycling hair follicle as an ideal systems biology research model / Exp Dermatol 19:707~713
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Clarkson PM / 2000 / Antioxidants: what role do they play in physical activity and health / Am J Clin Nut 72 : 637 ~ 646
Esfandiari A / 2005 / The effects of tea polyphenolic compounds on hair loss among rodents / J National Med Assoc 97 (8) : 1165 ~ 1169
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