지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
To investigate the improving effects of white tea water extract on skin wrinkle, skin aging animal model was produced by the irradiation of UVB to the backs of hairless mice for 12 weeks. And then experimental materials were applied topically for 4 weeks. Six to seven weeks female SKH-1 hairless mice were divided into five groups including normal (N: no UVB), control (C: UVB + saline), positive control (PC: UVB + 0.01% retinoic acid), experimental 1 (E1: UVB + 1% white tea water extract) and experimental 2 (E2: UVB + 2% white tea water extract) groups, five animals each group. Wrinkles for the C group were formed as a pattern of deep furrows and thick crests. Whereas wrinkles for the PC, E1 and E2 groups were formed as a pattern of shallow furrows and thin crests. Collagen fibers in dermis of the C group were broken severely and the density was sparse. Whereas collagen fibers in the dermis of the PC, E1 and E2 groups were almost intact with a regular arrangement. Elastosis was found in the dermis of C group with the infiltration of degenerated and clotted elastin. As for the amount of matrix metalloproteinase-3 (MMP-3) expression, PC, E1 and E2 groups were significantly lower than the C group. Therefore, white tea water extract could be used practically for the inhibition or improvement of skin wrinkle induced by UVB irradiation in hairless mice.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
AOAC / 1995 / Association of official analytical chemists official methods of analysis (12th) : 127 ~ 130
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Camouse MM / 2009 / Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin / Exp Dermatol 18 (6) : 522 ~
Chiba K / 2003 / Characteristics of skin wrinking and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin / Skin Pharmacol App
Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N Engl J Med 337 (20) : 1419 ~ 1428
Blois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 181 : 1199 ~ 1200
Camouse MM / 2009 / Topical application of green and white tea extracts provides protection from solar-simulated ultraviolet light in human skin / Exp Dermatol 18 (6) : 522 ~
Chiba K / 2003 / Characteristics of skin wrinking and dermal changes induced by repeated application of squalene monohydroperoxide to hairless mouse skin / Skin Pharmacol App
Fisher GJ / 1997 / Pathophysiology of premature skin aging induced by ultraviolet light / N Engl J Med 337 (20) : 1419 ~ 1428
이 논문의 저자 정보
최근 본 자료
댓글(0)
0