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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: Extracorporeal life support (ECLS) is a term used to describe a number of modalities including extracorporeal membrane oxygenation (ECMO) to support cardiac and/or pulmonary systems. The purpose of this study is to review the available evidence regarding the effect of ECLS in patients with acute poisoning.
Methods: Electronic literature searches with PubMed, Embase, Cochrane library, and KoreaMed were conducted for identification of relevant studies addressing ECLS in treatment of acute poisoning. The literature search was conducted by two investigators in March, 2016 with publication language restricted to English and Korean. The toxic substance, technique of ECLS, and final outcome of each case were analyzed.
Results: The final analysis included 64 articles including 55 case reports. There were no articles classified according to a high level of evidence such as randomized trial and prospective cohort study. ECLS treatment was used in the management of patients poisoned with 36 unique substances. Venovenous ECMO was performed in 4 cases.
Among the reported cases, 10 patients died despite treatment with ECLS.
Conclusion: Evidence supporting ECLS for patients with acute poisoning is inadequate. However, many case reports suggest that early consideration of ECLS in poisoned patients with refractory cardiac arrest or hemodynamic compromise refractory to standard therapies may be beneficial.
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참고문헌 (68)
참고문헌 신청
Baud FJ / 2007 / Clinical review: aggressive management and extracorporeal support for drug-induced cardiotoxicity / Crit Care 11:207
Johnson NJ / 2013 / A review of emergency cardiopulmonary bypass for severe poisoning by cardiotoxic drugs / J Med Toxicol 9:54~60
Mowry JB / 2015 / 2014 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 32nd Annual Report / Clin Toxicol (Phila) 53:962~1147
Lai MW / 2006 / 2005 Annual Report of the American Association of Poison Control Centers’ national poisoning and exposure database / Clin Toxicol (Phila) 44:803~932
박진경 / 2015 / Management of Cyanide Intoxication with Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy / The Korean Journal of Critical Care Medicine 30(3):218~221
Johnson NJ / 2013 / A review of emergency cardiopulmonary bypass for severe poisoning by cardiotoxic drugs / J Med Toxicol 9:54~60
Mowry JB / 2015 / 2014 Annual Report of the American Association of Poison Control Centers’ National Poison Data System (NPDS): 32nd Annual Report / Clin Toxicol (Phila) 53:962~1147
Lai MW / 2006 / 2005 Annual Report of the American Association of Poison Control Centers’ national poisoning and exposure database / Clin Toxicol (Phila) 44:803~932
박진경 / 2015 / Management of Cyanide Intoxication with Extracorporeal Membrane Oxygenation and Continuous Renal Replacement Therapy / The Korean Journal of Critical Care Medicine 30(3):218~221
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