지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Recently, with the increase of meat production, high quality and safety of meat have been strongly emphasized by Korean consumers. Marbling in beef has been regarded as an important criterion deciding meat quality in Korea. The purpose of this study was to identify the transcriptional level of insulin-like growth factor-1 (IGF-1) in longissimus muscle samples of 46 Hanwoo. The level of IGF-1 transcripts was measured by real-time polymerase chain reaction (PCR) and molecular connection of IGF-1 was analyzed using the Pathway Studio program (Ver 9.0). Increase of marbling score (MS) induced increase of IGF-1 transcripts level in the muscle and there is a significant correlation (p<0.05) between IGF-1 mRNA expression and MS. The pathway study showed that IGF-1 genes are regulated in insulin, fatty acid synthase, leptin, and corticotrophin releasing hormone. These results suggest that IGF-1 might be used as a useful marker for the improvement of economic traits in Hanwoo.
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참고문헌 (22)
참고문헌 신청
Breier, B. H. / 1999 / Regulation of protein and energy metabolism by the somatotropic axis / Domest. Anim. Endocrinol 17 : 209 ~ 218
Butler, S. T. / 2003 / Insulin restores GH responsiveness during lactation-induced negative energy balance in dairy cattle: effects on expression of IGF-1 and GH receptor 1A
Cesar, A. S. / 2014 / composition in Nellore cattle / BMC Genet 15 (1) : 39 ~
Daughaday, W. H. / 1989 / Insulin-like growth factors Ⅰ and Ⅱ peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentration / Endocr. Rev 10 : 68
Davis, M. E. / 1995 / Divergent selection for blood serum insulin-like growth factor 1 concentration in beer cattle / J. Anim. Sci 73 : 1927 ~ 1932
Butler, S. T. / 2003 / Insulin restores GH responsiveness during lactation-induced negative energy balance in dairy cattle: effects on expression of IGF-1 and GH receptor 1A
Cesar, A. S. / 2014 / composition in Nellore cattle / BMC Genet 15 (1) : 39 ~
Daughaday, W. H. / 1989 / Insulin-like growth factors Ⅰ and Ⅱ peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentration / Endocr. Rev 10 : 68
Davis, M. E. / 1995 / Divergent selection for blood serum insulin-like growth factor 1 concentration in beer cattle / J. Anim. Sci 73 : 1927 ~ 1932
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