지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.7
- 수록면
- 249 - 255 (7page)
이용수
초록· 키워드
오류제보하기
Cadmium is a strong toxic heavy metal which presents in paints and liquid wastes and causes oxidative stress in fish. On the other hand, lead is widely used for different purposes, e.g. lead pipes, it targets vital organs such as liver and kidney causing biochemical alterations. The present study evaluates the effects of 60 days exposure to Cd and Pb either single or combined together in African catfish. Sixty-four fishes were divided into 3 groups and exposed to CdCl₂ (7.02 mg/L) or PbCl₂ (69.3 mg/L) or a combination of them along with control group. Activities of acid phosphatase (ACP), lactate dehydrogenase (LDH) and glucose-6-phosphate dehydrogenase (G-6- PDH) were estimated. Moreover, gill, liver and kidney were assayed for activities of superoxide dismutase (SOD), catalase (CAT) and levels of glutathione (GSH) and malondialdehyde (MDA). Individual exposure showed that both Cd and Pb significantly decreased LDH activity and SOD activity in the kidney. Pb significantly increased G-6-PDH activity and decreased GSH level in the gill. CAT activity in liver and kidney elevated significantly on Cd exposure while lead caused a significant depletion in the liver and significant elevation in the kidney. Both Cd and Pb significantly increased MDA levels in liver and kidney while Pb increased its level in gills. The combined exposure resulted in normalization of LDH, G-6-PDH activity, and CAT activity in liver and kidney as well as GSH level in both tissues and MDA in gill and kidney. The combination increased SOD activity and MDA level in liver and decreased SOD activity in kidney and GSH level in gills. In conclusion, the antioxidant system of African catfish was adversely affected by prolonged exposure to Cd and Pb. The combined exposure caused less damage than individual exposure and returned most parameters to those of controls.
목차
Abstract
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (47)
참고문헌 신청
Mahurpawar, M. / 2015 / Effects of heavy metals on human health / Int. J. Res. Granthaalayah :1~7
Perez, M. / 2004 / Differences in prey capture in grass shrimp, Palaemonetes pugio, collected along an environmental impact gradient / Arch. Environ. Contam. Toxicol 46:81~89
Ryan, P.B. / 2000 / Longitudinal investigation of exposure to arsenic, cadmium, and lead in drinking water / Environ. Health Perspect 108:731
Flora, G. / 2012 / Toxicity of lead: a review with recent updates / Interdiscip. Toxicol 5:47~58
Jhamtani, R.C. / 2017 / Evaluation of acute effects of lead at sub-lethal concentrations in zebrafish / Res. J. Environ. Toxicol 11:97~103
Perez, M. / 2004 / Differences in prey capture in grass shrimp, Palaemonetes pugio, collected along an environmental impact gradient / Arch. Environ. Contam. Toxicol 46:81~89
Ryan, P.B. / 2000 / Longitudinal investigation of exposure to arsenic, cadmium, and lead in drinking water / Environ. Health Perspect 108:731
Flora, G. / 2012 / Toxicity of lead: a review with recent updates / Interdiscip. Toxicol 5:47~58
Jhamtani, R.C. / 2017 / Evaluation of acute effects of lead at sub-lethal concentrations in zebrafish / Res. J. Environ. Toxicol 11:97~103
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UCI(KEPA) : I410-ECN-0101-2019-513-000862836