지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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In the present study, we investigated biological activities of Rosa davurica Pall. leaves in order to evaluate thepossibility as a natural biomaterial. The 80% ethanol extract and its subsequent fractions of Rosa davurica Pall. leaves wereprepared using several solvents with different polarities. The extraction yield was 33.4, 36.6, 25.2, 18.7, 5.8 and 5.8% in ethanolextract, aqueous, butanol, ethyl acetate, n-hexane, chloroform fractions, respectively. The ethyl acetate fraction(661.38 ㎎/g), butanol fraction (396.68 ㎎/g) and 80% ethanolic extract (239.54 ㎎/g) has higher total polyphenol contentsthan other fractions. The antioxidant activity was detected in ethanolic extract, ethyl acetate and butanol fractions. Theethyl acetate fraction showed the highest levels of DPPH radical scavenging activity (IC50, 4.77 ㎍/㎖). Moreover, the ethylacetate fraction significantly inhibited production of NO in LPS-stimulated macrophage RAW 264.7 cells without cytotoxicity.
These results indicate that 80% ethanol extract and its fractions of Rosa davurica Pall. leaf, especially ethyl acetate fraction,have the properties of anti-oxidant and anti-inflammation, suggesting leaf of Rosa davurica Pall. may be a candidate fornatural and functional materials.
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참고문헌 (29)
참고문헌 신청
Bickers DR / 2006 / Oxidative stress in the pathogenesis of skin disease / Journal of Investigative Dermatology 126:2565~2575
Cencioni C / 2013 / Oxidative stress and epigenetic regulation in ageing and age-related diseases / International Journal of Molecular Sciences 14:17643~17663
Chawla A / 2011 / Macrophagemediated inflammation in metabolic disease / Nature Reviews Immunology 11:738~749
최경희 / 2013 / 국내 자생 민들레 5종의 항산화 활성 및 Nitric Oxide 생성억제 활성 / 한국약용작물학회지 21(3):191~196
Donnelly JK / 1989 / Superoxide dismutase in food / Food Chemistry 33:243~270
Cencioni C / 2013 / Oxidative stress and epigenetic regulation in ageing and age-related diseases / International Journal of Molecular Sciences 14:17643~17663
Chawla A / 2011 / Macrophagemediated inflammation in metabolic disease / Nature Reviews Immunology 11:738~749
최경희 / 2013 / 국내 자생 민들레 5종의 항산화 활성 및 Nitric Oxide 생성억제 활성 / 한국약용작물학회지 21(3):191~196
Donnelly JK / 1989 / Superoxide dismutase in food / Food Chemistry 33:243~270
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UCI(KEPA) : I410-ECN-0101-2019-480-000586444