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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
한국약용작물학회 한국약용작물학회지 한국약용작물학회지 제18권 제6호
발행연도
2010.12
수록면
421 - 428 (8page)

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The bark of Berberis koreana Palibin was fermented by Bifidobacterium longum B6 and Lactobadilus paracasei at 37℃ for 72 hour, then extracted by water solvent at 100℃ for 180 min. Total pholyphenol and flavonoid contents were improved by fermentation process, compared to conventional water extraction. The barks of B. koreana Palibin extracts by B. longum B6 (FE-B.L.) and by L. paracasei (FE-L.P.) showed 17% and 16% cytotoxicity on human normal cell lines(HEK293) at 1.0 mg/mℓ of the highest concentration, respectively, which was about 3-5% lower than 20% from normal extracts (NE). DPPH radical scavenging activity of the FE-B.L. and FE-L.P. were about 73% and 75.9% higher than 56.8% of NE. The highest inhibitory potency on xathine oxidase and superoxide dismutase (SOD)-like activities were also measured as 31.9% and 61.9% by adding FE-L.P. of 1.0 mg/mℓ. On tyrosinase inhibition test, the FE-L.P. showed highest activity as 75.9% at 1.0 mg/mℓ. Generally, FE-L.P. showed higher antioxidant activities as well as higher tyrosinase inhibition activity, possibly due to high contents of total pholyphenol and flavonoid. In general, fermentation of barks of B. koreana, Palibin has relatively better biological activities than normal extracts. Specifically, the extracts fermented by L. paracasei showed higher activities than that from B. longum B6.

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UCI(KEPA) : I410-ECN-0101-2019-480-000589369