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지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.12
- 수록면
- 409 - 415 (7page)
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이 논문의 연구 히스토리 (4)
2011
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초록· 키워드
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In this study, the bioactivities of ethanol (EELS) and water extract (WELS) from the leaf of Lythrum salicaria L. were investigated. In the anti-cancer activity, the growths of both human prostate cancer (DU145) and human colonic carcinoma cell (HT29) were inhibited up 60% by adding 10 mg/mℓ of EELS. Anti-inflammatory activity of EELS and WELS have been evaluated on lipopolysaccharide (LPS) induced release of nitric oxide (NO) by the macrophage RAW 264.7 cells. EELS and WELS inhibited inflammatory by 57.3 and 46.9% in 10 mg/mℓ, respectively. In the anti-oxidative activity, IC50 of DPPH radical scavenging activity was respectively 60.71 and 92.90 μg/mℓ by EELS and WELS. In the anti-diabetic activity, IC50 of α-amylase inhibitory activity of EELS and WELS were respectively 5,250 and 5,020 μg/mℓ. IC<sub>50</sub> of α-glucosidase inhibitory activity was 7.96 and 68.41 μg/mℓ by EELS and WELS. In the anti-obesity, IC<sub>50</sub> of lipase inhibitory activity was 880 and 9,840 μg/mℓ by EELS and WELS. Finally, EELS and WELS exhibited anti-oxidative, anti-inflammatory, anti-diabetic activity and anti-obesity. It suggests that Lythrum salicaria L. could be potentially used as a resource of bioactive materials for health functional foods.
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참고문헌 (27)
참고문헌 신청
Bae JH / 2009 / Physiological activity of methanol extracts from Ligularia fischeri and their hyperplasia inhibition activity of cancer cell / Journal of Bio-Environment Control 18:67~73
Bai G / 2004 / Screening α-glucosidase inhibitors in traditional chinese medicines / Acta Scientiarum Naturalium Universitatis Nankaiensis 37:98~102
Becker H / 2005 / Bioactivity guided isolation of antimicrobial compounds from Lythrum salicaria / Fitoterapia 7:580~584
Bitou N / 1999 / Screening of lipase inhibitors from marline algae / Lipids 34:441~445
Biois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 26:1198~1201
Bai G / 2004 / Screening α-glucosidase inhibitors in traditional chinese medicines / Acta Scientiarum Naturalium Universitatis Nankaiensis 37:98~102
Becker H / 2005 / Bioactivity guided isolation of antimicrobial compounds from Lythrum salicaria / Fitoterapia 7:580~584
Bitou N / 1999 / Screening of lipase inhibitors from marline algae / Lipids 34:441~445
Biois MS / 1958 / Antioxidant determination by the use of a stable free radical / Nature 26:1198~1201
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UCI(KEPA) : I410-ECN-0101-2019-480-000589389