지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.12
- 수록면
- 62 - 72 (11page)
이용수
초록· 키워드
오류제보하기
An active ingredient with hyaluronidase (HAse) inhibitory effect is one of the anti-aging approaches in cosmeceuticals. Here, red sea cucumbers (RSCs), Stichopus japonicus, from Jeju Island were evaluated to examine their HAse inhibitory and antioxidant activity effect. In this study, RSCs were extracted by six enzymatic hydrolysis (Alcalase; Al, Trypsin; Try, Neutrase; Neu, Pepsin; Pep, Alpha-chymotrypsin; Chy and Protamex; Pro). Alcalase hydrolysate (AlH) showed the highest antioxidant capacities for both of oxygen radical absorbance capacity (ORAC) and trolox equivalent antioxidant capacity (TEAC) methods, compared to those of other hydrolysates, at 66.59±0.78 μM TE/mg and 135.78±3.24 μM TE/㎎, respectively. Furthermore, AlH performed the highest capacity of HAse inhibitory with IC<SUB>50</SUB> value of 3.21 ㎎/ml. Thus, RSCs hydrolyzed by Al were chosen to determine the cellular antioxidant activity and hyaluronic acid (HA) production effect on Human immortalized keratinocyte cell line (HaCaT). The results showed that AlH improved the cell viabilities and intracellular reactive oxygen species (ROS) induced by 2,2’-Azobis(2-amidinopropane) dihydrochloride (AAPH) were significantly decreased. In addition, AlH increased HA amount by regulating HYAL2 and HAS2 expressions in the HaCaT cells. Taken together, AlH of RSCs collected from Jeju Island showed HAse inhibitory and antioxidant activities against skin-aging which shows its potentials can be an optional natural bioactive ingredient for novel cosmeceuticals.
목차
Abstract
Introduction
Materials and Methods
Results
Discussion
References
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
홍해삼 추출물의 멜라닌 형성 억제를 통한 미백효과 및 피부 재생효과에 관한 연구
생명과학회지
2018 .06
-
비스페놀A 유도 간 손상 마우스에서 해삼(Stichopus japonicas) 추출물 및 가수분해물의 간 기능 개선 효과
한국해양바이오학회지
2022 .12
-
Genomic Study of Cosmeceutical Producing Bacterial Strains from Jeju Island
한국미생물학회 학술대회논문집
2018 .04
-
Red Sea Cucumber (Stichopus japonicus) Suppresses Cancer Progression by Promoting the ROS-Mediated Inhibition of the MAPK Pathway
한국해양바이오학회지
2020 .12
-
A Study on the Tyrosinase Inhibitory and Antioxidant Effect of Microalgae Extracts
한국미생물·생명공학회지
2021 .01
-
다기능 해양소재로서 홍해삼의 효능과 지역별 성분 비교를 통한 활용 가능성 연구 고찰
한국해양바이오학회지
2020 .06
-
Whitening, Antioxidant, Anti-aging, and Antibacterial Activities of Streptomyces sp. T65 Extract and Synthesis of Mesoporous Nanoparticles for Cosmeceutical Formulations
한국미생물학회 학술대회논문집
2019 .04
-
Development of a New Type of Recombinant Hyaluronidase Using a Hexahistidine; Possibilities and Challenges in Commercialization
Journal of Microbiology and Biotechnology
2019 .01
-
Protective Effects of the Postbiotic Levilactobacillus brevis BK3 against H 2 O 2 -Induced Oxidative Damage in Skin Cells
Journal of Microbiology and Biotechnology
2024 .07
-
Characterization of Recombinant Bovine Sperm Hyaluronidase and Identification of an Important Asn-X-Ser/Thr Motif for Its Activity
Journal of Microbiology and Biotechnology
2018 .01
-
Evaluation of the Cosmeceutical Potential of Nannochloropsis sp. Extract
한국미생물학회 학술대회논문집
2022 .10
-
In Vivo/In Vitro Properties of Novel Antioxidant Peptide from Pinctada fucata
Journal of Microbiology and Biotechnology
2021 .01
-
Whole-Body Microbiota of Sea Cucumber (Apostichopus japonicus) from South Korea for Improved Seafood Management
Journal of Microbiology and Biotechnology
2017 .01
-
Bitter taste receptors protect against skin aging by inhibiting cellular senescence and enhancing wound healing
Nutrition Research and Practice
2022 .02
-
Bitter taste receptors protect against skin aging by inhibiting cellular senescence and enhancing wound healing
Nutrition Research and Practice
2022 .02
-
Antioxidant Activity of Manno-oligosaccharides Derived from the Hydrolysis of Polymannan by Extracellular Carbohydrase of Bacillus N3
한국해양바이오학회지
2018 .06
-
Functional Study of the Fermented Dahlia Extract Using Specific Environment-derived Bacteria as Active Ingredient in Cosmeceuticals
한국미생물학회 학술대회논문집
2022 .10
-
Isolation of a Potential Probiotic Levilactobacillus brevis and Evaluation of Its Exopolysaccharide for Antioxidant and α-Glucosidase Inhibitory Activities
Journal of Microbiology and Biotechnology
2024 .01
-
갯완두(Lathyrus japonicus) 에탄올 추출물의 항산화 및 항염증 효능
한국해양바이오학회지
2023 .06
-
MODIS AOD를 이용한 지상 시정 산출
대한원격탐사학회지
2017 .04
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0