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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국고분자학회 폴리머 폴리머 제42권 제6호
- 발행연도
- 2018.11
- 수록면
- 982 - 993 (12page)
- DOI
- 10.7317/pk.2018.42.6.982
이용수
초록· 키워드
오류제보하기
Bone tissue engineering is now used as an alternative for the treatment of bone-related diseases. In this study, chitosan-gelatin scaffold with olibanum microspheres containing dexamethasone has been produced by the freeze-drying method. SEM and FTIR were used to characterize the scaffolds synthesized. The rate of drug release from these scaffolds was measured by a UV spectrophotometer. The synthesized scaffold was measured in terms of the swelling and degradation rates. In vitro studies were conducted to evaluate bioactivity and the environmental compatibility of the scaffold with an MTT test. A good controlled release was achieved. The bioactivity analysis confirmed the formation of apatite. The results of the MTT test showed that the synthesized scaffold was biocompatible and had an appropriate interaction with the cell. The results showed that the produced scaffold had the properties necessary to regenerate and repair bones.
목차
Abstract
Introduction
Experimental
Results and Discussion
Conclusions
References
참고문헌 (53)
참고문헌 신청
[단행본] - B. Ratner / 2014 / Biomaterials Science: an Introduction / Academic Press
[학술지(정기간행물)] - F. Ghorbani / 2016 / / Mater. Sci. Eng. C 69 : 208 ~
[학술지(정기간행물)] - K. Maji / 2016 / / Int. J. Biomater. 2016 : 1 ~
[학술지(정기간행물)] - J. Wu / 2011 / / Carbohydr. Polym 86 : 1048 ~
[학술지(정기간행물)] - I. R. Serra / 2015 / / Mater. Sci. Eng. C 55 : 592 ~
[학술지(정기간행물)] - F. Ghorbani / 2016 / / Mater. Sci. Eng. C 69 : 208 ~
[학술지(정기간행물)] - K. Maji / 2016 / / Int. J. Biomater. 2016 : 1 ~
[학술지(정기간행물)] - J. Wu / 2011 / / Carbohydr. Polym 86 : 1048 ~
[학술지(정기간행물)] - I. R. Serra / 2015 / / Mater. Sci. Eng. C 55 : 592 ~
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UCI(KEPA) : I410-ECN-0101-2019-578-000116496