지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.9
- 수록면
- 275 - 279 (5page)
이용수
초록· 키워드
오류제보하기
Inflammatory bowel disease (IBD) is increasing in prevalence in developed countries but the cause of this increase is unclear. In animal models of IBD and in human IBD patients, alterations in the tight junctional proteins have been observed, suggesting that the intestinal microflora may penetrate the underlying colonic tissue and promote inflammation. Enterotoxigenic Bacteroides fragilis (ETBF) causes inflammatory diarrhea in human and is implicated in inflammatory bowel diseases. However, it is unclear whether alterations in tight junctional proteins occur during ETBF infection in mice. In this brief communication, we report that ETBF infection induces up-regulation of claudin-2 and down-regulation of claudin-5 through B. fragilis toxin (BFT) activity in the large intestine of C57BL/6 mice. In contrast, BFT did not induce changes in tight junctional proteins in the HT29/C1 cell line, suggesting that analysis of biological activity of BFT in vivo is important for evaluating ETBF effects.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
[학술지(정기간행물)] - Burek M / 2010 / Claudin-5 as a novel estrogen target in vascular endothelium / Arteriosclerosis, Thrombosis, and Vascular Biology 30 : 298 ~ 304
[학술지(정기간행물)] - Capaldo CT / 2009 / Cytokine regulation of tight junctions / Biochimica et Biophysica Acta 1788 : 864 ~ 871
[학술지(정기간행물)] - Chambers FG / 1997 / Bacteroides fragilis toxin exhibits polar activity on monolayers of human intestinal epithelial cells (T84 cells) in vitro / Infection and Immunity 65 : 3561 ~ 3570
[학술지(정기간행물)] - Chiba H / 2008 / Transmembrane proteins of tight junctions / Biochimica et Biophysica Acta 1778 : 588 ~ 600
[학술지(정기간행물)] - Eastaff-Leung N / 2010 / $Foxp3^{+}$ regulatory T cells, Th17 effector cells, and cytokine environment in inflammatory bowel disease / Journal of Clinical Immunology 30 : 80 ~ 89
[학술지(정기간행물)] - Capaldo CT / 2009 / Cytokine regulation of tight junctions / Biochimica et Biophysica Acta 1788 : 864 ~ 871
[학술지(정기간행물)] - Chambers FG / 1997 / Bacteroides fragilis toxin exhibits polar activity on monolayers of human intestinal epithelial cells (T84 cells) in vitro / Infection and Immunity 65 : 3561 ~ 3570
[학술지(정기간행물)] - Chiba H / 2008 / Transmembrane proteins of tight junctions / Biochimica et Biophysica Acta 1778 : 588 ~ 600
[학술지(정기간행물)] - Eastaff-Leung N / 2010 /
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Antimicrobial Susceptibility of Clinical Isolates of Bacteroides fragilis Group Organisms Recovered from 2009 to 2012 in a Korean Hospital
Annals of Laboratory Medicine
2015 .01
-
[Erratum]Antimicrobial Susceptibility of Clinical Isolates of Bacteroides fragilis Group Organisms Recovered from 2009 to 2012 in a Korean Hospital
Annals of Laboratory Medicine
2015 .01
-
복막염 환자에서 분리된 Bacteroides nordii 1예와 Bacteroides salyersiae 2예
Laboratory Medicine Online
2016 .01
-
The Impact of Diesel Exhaust Particles on Tight Junctional Proteins on Nose and Lung in a Mouse Model
Allergy, Asthma & Immunology Research
2021 .01
-
Dientamoeba fragilis Infection in Patients with Digestive and Non-Digestive Symptoms: A Case-Control Study
Parasites, Hosts and Diseases
2020 .04
-
Claudin-1, -2, -4, and -5: comparison of expression levels and distribution in equine tissues
Journal of Veterinary Science
2016 .12
-
The Role of Barrier Dysfunction and Change of Claudin Expression in Inflammatory Bowel Disease
Gut and Liver
2015 .01
-
Expression Pattern and Prognostic Significance of Claudin 1, 4 and 7 in Pancreatic Cancer
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Recent updates on the basic mechanisms and pathogenesis of inflammatory bowel diseases in experimental animal models
Intestinal research
2020 .01
-
우리나라 염증장질환의 현황
대한의사협회지
2021 .09
-
Update on the epidemiology of inflammatory bowel disease in Asia: where are we now?
Intestinal research
2022 .04
-
Pathogenesis of Inflammatory Bowel Disease and Recent Advances in Biologic Therapies
Immune Network
2017 .02
-
장내 미생물과 염증장질환
대한의사협회지
2021 .09
-
Fusobacterium Isolates Recovered From Colonic Biopsies of Inflammatory Bowel Disease Patients in Korea
Annals of Laboratory Medicine
2016 .01
-
Novel inflammatory bowel disease (IBD) specific electronic medical record allows scalable auditing of IBD severity, therapy and complications to show the current unmet need in IBD care
Intestinal research
2022 .10
-
Anti-inflammatory diet and inflammatory bowel disease: what clinicians and patients should know?
Intestinal research
2021 .01
-
Effects of 17β-Estradiol on Colonic Permeability and Inflammation in an Azoxymethane/Dextran Sulfate Sodium-Induced Colitis Mouse Model
Gut and Liver
2018 .01
-
Association of Inflammatory Bowel Disease (IBD) with Depressive Symptoms in the United States Population and Independent Predictors of Depressive Symptoms in an IBD Population: A NHANES Study
Gut and Liver
2017 .07
-
Immunological pathogenesis of inflammatory bowel disease
Intestinal research
2018 .01
-
염증장질환의 역학 및 진단
대한의사협회지
2021 .09
이 논문의 저자 정보
이 논문과 함께 이용한 논문
최근 본 자료
댓글(0)
0
UCI(KEPA) : I410-ECN-0101-2018-510-003599420